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Rabbit polyclonal to ACADL - N-terminal
Predicted to work with:
Recombinant fragment corresponding to a region within N-terminal amino acids 1-134 of Human ACADL (Uniprot ID: P28330).
Human hepatoma tissue; H1299 and HCT116 whole cell lysates.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 78% PBS, 20% Glycerol, 1% BSA
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 48 kDa.
1/100 - 1/1000.
Lipid metabolism; mitochondrial fatty acid beta-oxidation.
Involvement in disease
Defects in ACADL are a cause of acyl-CoA dehydrogenase very long-chain deficiency (ACADVLD) [MIM:201475]. An inborn error of mitochondrial fatty acid beta-oxidation which leads to impaired long-chain fatty acid beta-oxidation. It is clinically heterogeneous, with three major phenotypes: a severe childhood form characterized by early onset, high mortality and high incidence of cardiomyopathy; a milder childhood form with later onset, characterized by hypoketotic hypoglycemia, low mortality and rare cardiomyopathy; an adult form, with isolated skeletal muscle involvement, rhabdomyolysis and myoglobinuria, usually triggered by exercise or fasting.
Belongs to the acyl-CoA dehydrogenase family.
Information by UniProt
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACADL antibody - N-terminal (ab152160)
Immunohistochemical analysis of paraffin-embedded Human hepatoma tissue, staining ACADL using ab152160 at a 1/500 dilution.
Western blot - Anti-ACADL antibody - N-terminal (ab152160)
All lanes : Anti-ACADL antibody - N-terminal (ab152160) at 1/1000 dilution Lane 1 : H1299 whole cell lysate Lane 2 : HCT116 whole cell lysate Lysates/proteins at 30 µg per lane. Predicted band size: 48 kDa 10% SDS PAGE
has not yet been referenced specifically in any publications.
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