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Products:Signal Transduction >> Metabolism >> Mitochondrial
Overview
Product name
Anti-ACADM antibody
See all ACADM products (10) ...
Description
Rabbit polyclonal to ACADM
Tested applications
ELISA, WBmore details
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse, Rat, Cow, Chimpanzee
Immunogen
Synthetic peptide: AAGFGRCCRV LRSISRFHWR SQHTKANRQR EPGLGFSFEF TEQQKEFQAT, corresponding to N terminal amino acids 1-50 of Human ACADM
AAGFGRCCRV LRSISRFHWR SQHTKANRQR EPGLGFSFEF TEQQKEFQAT
Positive control
721_B cell lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 2% Sucrose, PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
-
Western blot - ACADM antibody (ab80303)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab80303 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
- 1 Image
WB
Application notes
ELISA: Use at an assay dependent dilution. Titre using peptide based assay: 1/1562500.
WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 46 kDa
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
This enzyme is specific for acyl chain lengths of 4 to 16.
Pathway
Lipid metabolism; mitochondrial fatty acid beta-oxidation.
Involvement in disease
Defects in ACADM are the cause of acyl-CoA dehydrogenase medium-chain deficiency (ACADMD) [MIM:201450]. It is an autosomal recessive disease which causes fasting hypoglycemia, hepatic dysfunction, and encephalopathy, often resulting in death in infancy.
Sequence similarities
Belongs to the acyl-CoA dehydrogenase family.
Cellular localization
Mitochondrion matrix.
Target information above from: UniProt accessionP11310
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- mitochondrial antibody
- ACAD 1 antibody
- ACAD1 antibody
see all
Database links
- Entrez Gene: 505968 Cow
- Entrez Gene: 34 Human
- Entrez Gene: 11364 Mouse
- Entrez Gene: 24158 Rat
- Omim: 607008 Human
- SwissProt: P11310 Human
- SwissProt: P45952 Mouse
- SwissProt: P08503 Rat
see all
Anti-ACADM antibody images:
Western blot - ACADM antibody (ab80303)
Anti-ACADM antibody (ab80303) at 1 µg/ml + 721_B cell lysate at 10 µg
Secondary
HRP-conjugated anti-Rabbit IgG at 1/50000 dilution
Predicted band size : 46 kDa
Observed band size : 40 kDa (why is the actual band size different from the predicted?)
References for Anti-ACADM antibody (ab80303)
ab80303 has not yet been referenced specifically in any publications.
Publishing research using ab80303? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"