Anti-ACADM antibody (ab94951)

Overview

• Product nameAnti-ACADM antibodySee all ACADM primary antibodies ...
• Description
  Rabbit polyclonal to ACADM
• Tested applicationsWB, IHC-P more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse, Rat
• Immunogen

  Recombinant fragment, corresponding to amino acids 186-417 of Human ACADM (NM_000016).

• Positive controlHuman fetal skin and fetal heart lysates; Human fetal kidney tissue

Properties

• FormLyophilised:Reconstitute in 200ul sterile H2O.
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.02% Sodium Azide
  
• Concentration information loading...
• PurityProtein A purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  • Lipid metabolism

  • Metabolism
  • Pathways and Processes
  • Mitochondrial Metabolism
  • Mitochondrial markers

  • Metabolism
  • Pathways and Processes
  • Redox metabolism
  • Fatty acid oxidation

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of lipids and lipoproteins

  • Signal Transduction
  • Metabolism
  • Lipid metabolism

  • Signal Transduction
  • Metabolism
  • Mitochondrial

  • Cardiovascular
  • Lipids / Lipoproteins
  • Fatty Acids
  • Metabolism

Applications

Target

• FunctionThis enzyme is specific for acyl chain lengths of 4 to 16.
• PathwayLipid metabolism; mitochondrial fatty acid beta-oxidation.
• Involvement in diseaseDefects in ACADM are the cause of acyl-CoA dehydrogenase medium-chain deficiency (ACADMD) [MIM:201450]. It is an autosomal recessive disease which causes fasting hypoglycemia, hepatic dysfunction, and encephalopathy, often resulting in death in infancy.
• Sequence similaritiesBelongs to the acyl-CoA dehydrogenase family.
• Cellular localizationMitochondrion matrix.

Target information above from: UniProt accession P11310 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 34 Human
  • Entrez Gene: 11364 Mouse
  • Entrez Gene: 24158 Rat
  • Omim: 607008 Human
  • SwissProt: P11310 Human
  • SwissProt: P45952 Mouse
  • SwissProt: P08503 Rat
  • Unigene: 445040 Human

  • Unigene: 10530 Mouse
  • Unigene: 6302 Rat

  see all

• Alternative names
  ACAD 1 antibodyACAD1 antibodyAcadm antibody

  ACADM_HUMAN antibodyAcyl coenzyme A dehydrogenase antibodyAcyl coenzyme A dehydrogenase C 4 to C 12 straight chain antibodyFLJ18227 antibodyFLJ93013 antibodyFLJ99884 antibodyMCAD antibodyMCADH antibodyMedium chain acyl CoA dehydrogenase antibodyMedium chain fatty acyl CoA dehydrogenase antibodyMedium chain specific acyl CoA dehydrogenase antibodyMedium chain specific acyl CoA dehydrogenase mitochondrial antibodyMedium-chain specific acyl-CoA dehydrogenase antibodymitochondrial antibody

  see all

Anti-ACADM antibody images

• 

  Western blot - ACADM antibody (ab94951)
  All lanes : Anti-ACADM antibody (ab94951) at 1/100 dilution
  
  Lane 1 : Human fetal skin lysate
  Lane 2 : Human fetal heart lysate
  
  
  Predicted band size : 47 kDa
  
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ACADM antibody (ab94951)
  ab94951, at 1/100 dilution, showing cytoplasmic staining of ACADM in formalin-fixed, paraffin-embedded Human fetal kidney tissue by Immunohistochemistry.