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Overview

  • Product nameACADM proteinSee all ACADM proteins and peptides ...
  • Protein descriptionRecombinant Human full length ACADM (amino acids 26-421) with a N terminal His tag; a single, non-glycosylated polypeptide chain; 417 amino acids with tag; predicted Mwt: 45.9 kDa (UniProt P11310).
  • Uniprot accessionP11310
  • Molecular weight45.900kDa
  • Protein length396 amino acids
  • Expression hostE. coli

    • Properties

  • Purity> 90 % by SDS-PAGE
  • E.C. Number1.3.99.3
  • FormLiquid
  • Storage instructionsPlease see Notes section
  • Storage bufferpH: 7.50
    Constituents: 20% Glycerol, 0.32% Tris HCl
  • Concentration information loading...
  • Additional notesalthough stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
  • Sequence notesMGSSHHHHHH SSGLVPRGSH MKANRQREPG LGFSFEFTEQ QKEFQATARK FAREEIIPVA AEYDKTGEYP VPLIRRAWEL GLMNTHIPEN CGGLGLGTFD ACLISEELAY GCTGVQTAIE GNSLGQMPII IAGNDQQKKK YLGRMTEEPL MCAYCVTEPG AGSDVAGIKT KAEKKGDEYI INGQKMWITN GGKANWYFLL ARSDPDPKAP ANKAFTGFIV EADTPGIQIG RKELNMGQRC SDTRGIVFED VKVPKENVLI GDGAGFKVAM GAFDKTRPVV AAGAVGLAQR ALDEATKYAL ERKTFGKLLV EHQAISFMLA EMAMKVELAR MSYQRAAWEV DSGRRNTYYA SIAKAFAGDI ANQLATDAVQ ILGGNGFNTE YPVEKLMRDA KIYQIYEGTS QIQRLIVARE HIDKYKN
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab117199 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent concentration.
  • Application notesThis peptide can be used with studies using ab13677 and ab115277.

    • Protein info

    • Alternative names
        ACAD 1ACAD1Acadm
        ACADM_HUMANAcyl coenzyme A dehydrogenaseAcyl coenzyme A dehydrogenase C 4 to C 12 straight chainFLJ18227FLJ93013FLJ99884MCADMCADHMedium chain acyl CoA dehydrogenaseMedium chain fatty acyl CoA dehydrogenaseMedium chain specific acyl CoA dehydrogenaseMedium chain specific acyl CoA dehydrogenase mitochondrialMedium-chain specific acyl-CoA dehydrogenasemitochondrial
      see all
  • FunctionThis enzyme is specific for acyl chain lengths of 4 to 16.
  • PathwayLipid metabolism; mitochondrial fatty acid beta-oxidation.
  • Involvement in diseaseDefects in ACADM are the cause of acyl-CoA dehydrogenase medium-chain deficiency (ACADMD) [MIM:201450]. It is an autosomal recessive disease which causes fasting hypoglycemia, hepatic dysfunction, and encephalopathy, often resulting in death in infancy.
  • Sequence similaritiesBelongs to the acyl-CoA dehydrogenase family.
  • Cellular localizationMitochondrion matrix.

    • Target information above from: UniProt accession P11310 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for ACADM protein (ab117199)

    ab117199 has not yet been referenced specifically in any publications.

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