Overview

  • Product name
  • Description
    Rabbit polyclonal to ACAT1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Zebrafish
  • Immunogen

    Recombinant fragment within Zebrafish ACAT1 aa 2-164. The exact sequence is proprietary.
    Database link: Q6AZA0

  • Positive control
    • Whole zebrafish whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab210551 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 44 kDa.

Target

  • Function
    Plays a major role in ketone body metabolism.
  • Involvement in disease
    Defects in ACAT1 are a cause of 3-ketothiolase deficiency (3KTD) [MIM:203750]; also known as alpha-methylacetoaceticaciduria. 3KTD is an inborn error of isoleucine catabolism characterized by intermittent ketoacidotic attacks associated with unconsciousness. Some patients die during an attack or are mentally retarded. Urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, triglylglycine, butanone is increased. It seems likely that the severity of this disease correlates better with the environmental or acquired factors than with the ACAT1 genotype.
  • Sequence similarities
    Belongs to the thiolase family.
  • Cellular localization
    Mitochondrion.
  • Information by UniProt
  • Database links
    • Alternative names
      • ACAT 1 antibody
      • ACAT antibody
      • acat1 antibody
      • Acetoacetyl CoA thiolase antibody
      • acetoacetyl Coenzyme A thiolase antibody
      • Acetoacetyl-CoA thiolase antibody
      • Acetyl CoA acetyltransferase, mitochondrial antibody
      • Acetyl Coenzyme A acetyltransferase 1 antibody
      • Acetyl-CoA acetyltransferase antibody
      • acetyl-coa acetyltransferase precursor, mitochondrial antibody
      • Acetyl-CoA thiolase, mitochondrial antibody
      • acetyl-Coenzyme A acetyltransferase 1 antibody
      • MAT antibody
      • mitochondrial acetoacetyl-CoA thiolase antibody
      • mitochondrial antibody
      • RATACAL antibody
      • T2 antibody
      • testicular tissue protein Li 198 antibody
      • THIL antibody
      • THIL_HUMAN antibody
      see all

    Images

    • Anti-ACAT1 antibody (ab210551) at 1/1000 dilution + whole zebrafish whole cell lysate at 30 µg

      Predicted band size: 44 kDa



      10% SDS-PAGE

    References

    ab210551 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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