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Rabbit polyclonal to ACAT1
Recombinant fragment within Zebrafish ACAT1 aa 2-164. The exact sequence is proprietary.
Database link: Q6AZA0
Whole zebrafish whole cell lysate.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol, 0.75% Glycine, 1.21% Tris
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 44 kDa.
Plays a major role in ketone body metabolism.
Involvement in disease
Defects in ACAT1 are a cause of 3-ketothiolase deficiency (3KTD) [MIM:203750]; also known as alpha-methylacetoaceticaciduria. 3KTD is an inborn error of isoleucine catabolism characterized by intermittent ketoacidotic attacks associated with unconsciousness. Some patients die during an attack or are mentally retarded. Urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, triglylglycine, butanone is increased. It seems likely that the severity of this disease correlates better with the environmental or acquired factors than with the ACAT1 genotype.
Belongs to the thiolase family.
Information by UniProt
ACAT 1 antibody
Western blot - Anti-ACAT1 antibody (ab210551)
Anti-ACAT1 antibody (ab210551) at 1/1000 dilution + whole zebrafish whole cell lysate at 30 µg
Predicted band size:
has not yet been referenced specifically in any publications.
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