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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ACAT1 antibody (ab78338)
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Product Name
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ACAT1 antibody
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See all ACAT1 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to ACAT1
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Immunogen
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Synthetic peptide: KMSLRNRLSKSRENPEED, corresponding to amino acids 6-23 of Human ACAT1
BLAST 'KMSLRNRLSKSRENPEED' with  or 
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Reacts with
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Hu, Ms, Rat, Pig
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Tested applications
(see key)
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ICC, IHC-P, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ICC: Use at an assay dependent dilution.
IHC-P: Use at a concentration of 5 µg/ml.
WB: Use at an assay dependent dilution. Predicted molecular weight: 45 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Adrenal tissue.
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Cellular localization
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Mitochondrial
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Research areas
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Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Signal Transduction >> Metabolism >> Mitochondrial
Signal Transduction >> Metabolism >> Amino Acids
Tags & Cell Markers >> Subcellular Markers >> Organelles >> Mitochondria
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Relevance
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ACAT1, acetoacetyl CoA thiolase, plays a major role in ketone body metabolism. It is a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in the gene encoding ACAT1 are associated with the alpha-methylacetoaceticaciduria disorder,an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, TBS, 0.5mg/ml BSA, pH 7.4 Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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Batch dependent within range: 0.20 - 0.25 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ACAT1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for ACAT1 antibody images, references, products related to ab78338 and other tools.
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ACAT1 antibody images:
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 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ACAT1 antibody (ab78338)
ab78338, at 5 µg/ml, staining ACAT1 in formalin-fixed, paraffin-embedded adrenal tissue by Immunohistochemistry.
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Search PubMed (MEDLINE) for references to ACAT1
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ACAT1 antibody - more information
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Customer reviews (feedback) regarding ACAT1 antibody |
Customer FAQs regarding ACAT1 antibody |
Protocols for ACAT1 antibody |
Price and availability of products related to ACAT1 antibody |
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ACAT1 antibody - related products:
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ACAT1 antibody - other tools:
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Contact Abcam with a Technical Enquiry about ACAT1 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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