|
|
|
|
|
Product Name
|
ACCN2 antibody - Extracellular domain
|
| |
See all ACCN2 antibodies (3)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Sheep polyclonal to ACCN2 - Extracellular domain
|
|
Immunogen
|
Synthetic peptide from the extracellular domain of rat ACCN2 conjugated to an immunogenic carrier protein.
|
|
Reacts with
(species key)
|
Hu, Ms, Rat
|
|
Specificity
|
ab81058 is specific for ACCN2.
|
|
Tested applications
(see key)
|
IHC-Fr, IHC-P, WB
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions
IHC-P: Use at a concentration of 10 - 50 µg/ml (antigen retrieval is recommended).
IHC-Fr: Use at a concentration of 10 - 50 µg/ml.
WB: Use at a concentration of 10 - 50 µg/ml. Predicted molecular weight: 60 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
|
|
Cellular localization
|
Cell Membrane; Multi-pass membrane protein
Note: Localizes in synaptosomes at dendritic synapses of neurons. Co-localizes with DLG4.
|
|
Research areas
|
Neuroscience >> Neurotransmission >> Receptors / Channels >> Sodium Channels
|
|
Relevance
|
ACCN2 belongs to the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN2 is expressed in most if not all brain neurons, and it may be an ion channel subunit; however, its function as an ion channel remains unknown. Alternative splicing of this gene generates 2 transcript products.
|
|
|
|
|
Database links
|
The links below go to external sites and will open in a new browser window |
|
Raised in
|
Sheep
|
|
Clonality
|
Polyclonal
|
|
Isotype
|
IgG
|
|
Purity
|
IgG fraction
|
|
Storage buffer
|
Preservative: None
Constituents: 1X PBS
|
|
Form
|
Lyophilised
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
|
|
Concentration
|
1.000 mg/ml
|
|
Storage instructions
|
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze / thaw cycles.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ACCN2 antibody - Extracellular domain is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
| |
|
Search PubMed (MEDLINE) for references to ACCN2
|
| |
ACCN2 antibody - Extracellular domain - more information
|
Customer reviews (feedback) regarding ACCN2 antibody - Extracellular domain |
Customer FAQs regarding ACCN2 antibody - Extracellular domain |
Protocols for ACCN2 antibody - Extracellular domain |
Price and availability of products related to ACCN2 antibody - Extracellular domain |
| |
ACCN2 antibody - Extracellular domain - related products:
|
|
|
| |
ACCN2 antibody - Extracellular domain - other tools:
|
Contact Abcam with a Technical Enquiry about ACCN2 antibody - Extracellular domain |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
