Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Signal Transduction >> Signaling Pathway >> Lipid Signaling >> Other
Overview
Product name
Anti-ACOT7 antibody
See all ACOT7 products (3) ...
Description
Rabbit polyclonal to ACOT7
Tested applications
WB, IHC-Pmore details
Cross reactivity
Reacts with
Mouse, Rat, Human
Immunogen
A synthetic peptide from near the C terminal residues of human ACOT7 (NM_181864).
Positive control
Human fetal brain lysate; human brain tissue.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 2% BSA
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Neuroscience >> Neurotransmission >> Intracellular Signaling >> Regulation
Signal Transduction >> Signaling Pathway >> Lipid Signaling >> Other
Applications
Show applications key
Our Abpromise guarantee covers the use of ab85151 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes
IHC-P: 1/50 - 1/200.
WB: 1/200 - 1/1000. Predicted molecular weight: 42 kDa.
Peptide ELISA: 1/40000 - 1/80000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May play an important physiological function in brain. May play a regulatory role by modulating the cellular levels of fatty acyl-CoA ligands for certain transcription factors as well as the substrates for fatty acid metabolizing enzymes, contributing to lipid homeostasis. Has broad specificity, active towards fatty acyl-CoAs with chain-lengths of C8-C18. Has a maximal activity toward palmitoyl-CoA.
Tissue specificity
Isoform 4 is expressed exclusively in brain.
Sequence similarities
Contains 2 acyl coenzyme A hydrolase domains.
Cellular localization
Cytoplasm and Mitochondrion.
Target information above from: UniProt accessionO00154
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- ACH1 antibody
- ACOT 7 antibody
- ACOT7 antibody
see all
Database links
- Entrez Gene: 11332 Human
- Entrez Gene: 70025 Mouse
- Entrez Gene: 26759 Rat
- Omim: 602587 Human
- SwissProt: O00154 Human
- SwissProt: Q91V12 Mouse
- SwissProt: Q64559 Rat
- Unigene: 126137 Human
see all
Anti-ACOT7 antibody images:
Western blot - ACOT7 antibody (ab85151)
Anti-ACOT7 antibody (ab85151) at 1/500 dilution + human fetal brain lysate
Predicted band size : 42 kDa
Observed band size : 42 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ACOT7 antibody (ab85151)
ab85151, at a 1/100 dilution, staining ACOT7 in formalin fixed, paraffin embedded human brain tissue by Immunohistochemistry.
References for Anti-ACOT7 antibody (ab85151)
ab85151 has not yet been referenced specifically in any publications.
Publishing research using ab85151? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"