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Overview

  • Product nameACTN3 protein (Tagged-His Tag)
  • Protein descriptionRecombinant fragment corresponding to amino acids 325-608 of Human ACTN3 with His-DHFR tag at N terminal; MWt 33.3 kDa excluding tag (BC099647; Q08043).
  • Uniprot accessionQ08043
  • Molecular weight33.300kDa
  • Protein length284 amino acids
  • Expression hostE. coli

    • Properties

  • Purification notesPurity determined to be 60% by SDS-PAGE.
  • FormLyophilised:Reconstitute with water to desired concentration.
  • Storage instructionsShipped at 4°C. Store at -20ºC.
  • Storage bufferConstituents: 0.32% Tris HCl, 0.58% Sodium chloride
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab127135 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        Actinin alpha 3actinin, alphaACTN 3
        ACTN3ACTN3_HUMANAlpha actinin skeletal muscleAlpha actinin skeletal muscle isoform 3Alpha-Actinin 3Alpha-actinin skeletal muscle isoform 3Alpha-actinin-3F actin cross linking proteinF-actin cross-linking proteinMGC117002MGC117005OTTHUMP00000219049OTTHUMP00000219054
      see all
  • FunctionF-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
  • Tissue specificityExpressed only in a subset of type 2 skeletal muscle fibers.
  • Sequence similaritiesBelongs to the alpha-actinin family.
    Contains 1 actin-binding domain.
    Contains 2 CH (calponin-homology) domains.
    Contains 2 EF-hand domains.
    Contains 4 spectrin repeats.

    • Target information above from: UniProt accession Q08043 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for ACTN3 protein (Tagged-His Tag) (ab127135)

    ab127135 has not yet been referenced specifically in any publications.

    Publishing research using ab127135 ? Please let us know so that we can cite the reference in this datasheet

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