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Product Name
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ADA antibody
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See all ADA antibodies (6)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to ADA
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Immunogen
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Adenosine Deaminase [Calf Spleen]
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Reacts with
(species key)
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Cow
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Tested applications
(see key)
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Dot
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Dot: 1/8000 - 1/40000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nuclear
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Research areas
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Cancer >> Cancer Metabolism >> Response to hypoxia
Chromatin and Nuclear Signaling >> Chromatin Modifying Enzymes >> Deamination
Chromatin and Nuclear Signaling >> DNA / RNA >> DNA / Nucleotides
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Relevance
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ADA (Adenosine deaminase) is an enzyme involved in the purine catabolic pathway. It irreversibly deaminates adenosine, converting it to the related nucleoside inosine by the removal of an amine group. Defects in ADA are a cause of autosomal recessive severe combined immuno-deficiency (SCID).
Assay by immunoelectrophoresis resulted in a single precipitin
arc against anti-Rabbit Serum as well as purified and partially purified Adenosine Deaminase [Calf Spleen]. Cross reactivity against Adenosine Deaminase from other tissues and species may occur but have not been
specifically determined.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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IgG fraction
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Storage buffer
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Preservative: 0.01% Sodium Azide
Constituents: 0.15M Sodium chloride, 0.02M Potassium phosphate. pH 7.2 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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This product is an IgG fraction antibody purified from monospecific antiserum by a multistep process which includes delipidation, salt fractionation and ion exchange chromatography followed by
extensive dialysis against the buffer.
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Form
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Liquid
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Concentration
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10.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ADA antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to ADA
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ADA antibody - more information
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Customer reviews (feedback) regarding ADA antibody |
Customer FAQs regarding ADA antibody |
Protocols for ADA antibody |
Price and availability of products related to ADA antibody |
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ADA antibody - related products:
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ADA antibody - other tools:
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Contact Abcam with a Technical Enquiry about ADA antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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