ADAM12 peptide (Aminoterminal end) (ab41204)
Constituents: 0.001% Tween 20, 30mM HEPES, 2mM EDTA, 150mM Sodium chloride, pH 6.75
Our Abpromise guarantee covers the use of ab41204 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
This peptide can be used with studies using ab39155. Dilution optimised using Chromogenic detection.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
- A disintegrin and metalloproteinase domain 12ADA12_HUMANADAM 12
- ADAM metallopeptidase domain 12ADAM12Disintegrin and metalloproteinase domain-containing protein 12MCMPMCMPMltnaMeltrin alphaMeltrin-alphaMLTNMLTNAOTTHUMP00000046766
Contains 1 EGF-like domain.
Contains 1 peptidase M12B domain.
The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
modificationsThe precursor is cleaved by a furin endopeptidase.
References for ADAM12 peptide (Aminoterminal end) (ab41204)
ab41204 has not yet been referenced specifically in any publications.