ADAM15 peptide (Propeptide domain) (ab41211)
Constituents: 0.001% Tween 20, 30mM HEPES, 2mM EDTA, 150mM Sodium chloride, pH 6.75
Our Abpromise guarantee covers the use of ab41211 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- A disintegrin and metalloproteinase domain 15A disintegrin and metalloproteinase domain 15ADA15_HUMAN
- ADAM 15ADAM metallopeptidase domain 15Adam15and cysteine-rich protein 15Disintegrin and metalloproteinase domain-containing protein 15disintegrin-likeEC 3.4.24.MDC 15MDC-15MDC15Metalloprotease RGD disintegrin proteinMetalloproteinase like disintegrin like and cysteine rich protein 15Metalloproteinase-likeMetargidin
Contains 1 EGF-like domain.
Contains 1 peptidase M12B domain.
Disintegrin domain binds to integrin alphaV-beta3.
The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
modificationsThe precursor is cleaved by a furin endopeptidase.
Phosphorylation increases association with PTKs.
References for ADAM15 peptide (Propeptide domain) (ab41211)
ab41211 has not yet been referenced specifically in any publications.