ADAM15 protein (Tagged) (ab131862)
Constituents: 0.31% Glutathione, 0.79% Tris HCl
Best used within three months from the date of receipt.
Our Abpromise guarantee covers the use of ab131862 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|SDS-PAGE||SDS-PAGE: Use at an assay dependent concentration.|
|ELISA||ELISA: Use at an assay dependent concentration.|
|WB||WB: Use at an assay dependent concentration.|
- A disintegrin and metalloproteinase domain 15ADA15_HUMANADAM 15
- ADAM metallopeptidase domain 15Adam15and cysteine-rich protein 15Disintegrin and metalloproteinase domain-containing protein 15disintegrin-likeEC 3.4.24.MDC 15MDC-15MDC15Metalloprotease RGD disintegrin proteinMetalloproteinase like disintegrin like and cysteine rich protein 15Metalloproteinase-likeMetargidin
Contains 1 EGF-like domain.
Contains 1 peptidase M12B domain.
Disintegrin domain binds to integrin alphaV-beta3.
The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
modificationsThe precursor is cleaved by a furin endopeptidase.
Phosphorylation increases association with PTKs.
References for ADAM15 protein (Tagged) (ab131862)
ab131862 has not yet been referenced specifically in any publications.