The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesWB: 1/1000 - 1/5000. Predicted molecular weight: 64 kDa. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
FunctionSperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.
Tissue specificityExpressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues.
A disintegrin and metalloproteinase domain 2 antibody
ADAM 2 antibody
ADAM metallopeptidase domain 2 antibody
Cancer/testis antigen 15 antibody
Disintegrin and metalloproteinase domain-containing protein 2 antibody
Fertilin beta antibody
Fertilin subunit beta antibody
PH 30 antibody
PH 30b antibody
Ph30 beta antibody
Anti-ADAM2 antibody images
Western blot - ADAM2 antibody (ab50642)
All lanes : Anti-ADAM2 antibody (ab50642) at 1/1000 dilution
Lane 1 : ST Lysate (treated with IL1-alpha)
at 25 µl Lane 2 : ST Lysate (treated with IL1-alpha)
at 20 µl Lane 3 : ST Lysate (treated with IL1-alpha)
at 15 µl Lane 4 : ST Lysate (treated with IL1-alpha)
at 10 µl