ADAM21 protein (Tagged) (ab132360)
Constituents: 0.31% Glutathione, 0.79% Tris HCl
Our Abpromise guarantee covers the use of ab132360 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||WB: Use at an assay dependent concentration.|
|SDS-PAGE||SDS-PAGE: Use at an assay dependent concentration.|
|ELISA||ELISA: Use at an assay dependent concentration.|
- A disintegrin and metalloproteinase domain 21ADA21_HUMANADAM 21
- ADAM metallopeptidase domain 21ADAM metallopeptidase domain 21, preproproteinAdam21ADAM31Disintegrin and metalloproteinase domain-containing protein 21
Contains 1 EGF-like domain.
Contains 1 peptidase M12B domain.
The cysteine-rich domain encodes putative cell-fusion peptides, which could be involved in sperm-egg fusion.
The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
modificationsHas no obvious cleavage site for furin endopeptidase, suggesting that the proteolytic processing is regulated.
References for ADAM21 protein (Tagged) (ab132360)
ab132360 has not yet been referenced specifically in any publications.