Anti-ADAM30 antibody - Metalloproteinase domain (ab40136)

Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab40136 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/1000 when using colorimetric substrates such as BCIP/NBT, 1/5000 for chemiluminescent substrates. Predicted molecular weight: 89 kDa. EDTA/EGTA treatment of tissues or lysates is required to see latent zymogen. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay be involved in spermatogenesis and fertilization.
    • Tissue specificityExpressed specifically in testis.
    • Sequence similaritiesContains 1 disintegrin domain.
      Contains 1 EGF-like domain.
      Contains 1 peptidase M12B domain.
    • DomainThe conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • A disintegrin and metallopeptidase domain 30 antibody
      • ADA30_HUMAN antibody
      • ADAM 30 antibody
      • ADAM metallopeptidase domain 30 antibody
      • ADAM30 antibody
      • Disintegrin and metalloproteinase domain-containing protein 30 antibody
      • EC 3.4.24.- antibody
      • MGC132801 antibody
      • MGC132802 antibody
      • OTTHUMP00000014034 antibody
      • Svph4 antibody
      see all

    References for Anti-ADAM30 antibody - Metalloproteinase domain (ab40136)

    ab40136 has not yet been referenced specifically in any publications.

    Product Wall

    Dear Cecil In response to your query, I'm afraid I can't provide you with more specific details on the peptide sequence because these amino acid sequences are proprietary. The only information I can provide you with is the following details: ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"