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Product Name
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ADAM33 peptide (Cytoplasmic domain)
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Product type
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Proteins and Peptides
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Peptide
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Synthetic peptide ADAM33.
This peptide was used as an immunogen for ab39193 - ADAM33 antibody - Cytoplasmic domain.
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Specificity
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We have a range of domain specific antibodies for this target. For a full list please see all ADAM33 antibodies
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Tested applications
(see key)
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ELISA, WB
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. This peptide can be used with studies using ab39193. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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Research areas
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Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Metalloprotease >> ADAMs
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> ADAM Protein Family
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> MMP
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Relevance
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ADAM33, also known as A disintegrin and metalloproteinase 33, is a member of the metalloproteinase family containing disintegrin-like domains (ADAMs). ADAM33 appears to be widely expressed and found in most organs. ADAM33 may act as a cell-attachment molecule, by binding integrins through the cysteine-rich domain. Recent work suggests that mutations in ADAM33 may be linked to asthma and that many of the mutations generate new cysteine residues, which may disturb the function of ADAM33.
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ADAM33 peptide (Cytoplasmic domain) (ab41229) |
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Purity
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>95% by SDS-PAGE
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Storage buffer
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Preservative: None
Constituents: 0.001% Tween 20, 30mM HEPES, 2mM EDTA, 150mM Sodium chloride, pH 6.75
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ADAM33 peptide (Cytoplasmic domain) is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to ADAM33
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ADAM33 peptide (Cytoplasmic domain) - more information
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