Recommended dilutions ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. This peptide can be used with studies using ab39152. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Members of ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. The extracellular region of ADAM8 shows significant amino acid sequence homology to hemorrhagic snake venom proteins, including the metalloprotease and disintegrin domains. The expression of ADAM8 is upregulated by retinoic acid and vitamin D3. The function of ADAM8 is still poorly understood. ADAM8 has been shown to stimulate osteoclasts, and to be produced by bone marrow cultures stimulated by vitamin-D. ADAM8 is involved in protein processing at the cell surface and is also thought to act as a leukocyte differentiation marker.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ADAM8 peptide (Propeptide domain) is on this datasheet. But please do contact us if you would like any reassurance!
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