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Anti-ADAM9 antibody - Propeptide domain (ab39175)

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Overview

Product name

Anti-ADAM9 antibody - Propeptide domain
See all ADAM9 products (9) ...

Description

Rabbit polyclonal to ADAM9 - Propeptide domain

Specificity

This antibody is specific for ADAM9, also known as MDC9 and Meltrin-g.

Tested applications

WB, ICC/IFmore details

Cross reactivity

Reacts with

Human

Immunogen

Synthetic peptide based on the amino end (propeptide)of human ADAM9.

Read Abcam's proprietary immunogen policy

(Peptide available as ab41161.)

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.05% Sodium Azide
Constituents: 50% Glycerol

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Purification notes

The antibody has been peptide-affinity purified.

Clonality

Polyclonal

Isotype

IgG

Research areas

Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Metalloprotease >> ADAMs
Cancer >> Invasion/microenvironment >> ECM >> Extracellular matrix >> ADAM protein family
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> ADAM Protein Family
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> MMP

Applications

Show applications key

Our Abpromise guarantee covers the use of ab39175 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

ADAM9 encodes disintegrin and metalloprotease (ADAM) domain 9, which is a member of the ADAM protein family. Members of this family are membrane- anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell- cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The member encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.

Cellular localization

Isoform 1: Cell membrane; single-pass type I membrane protein. Isoform 2: Secreted protein.

Alternative names

  • A disintegrin and metalloproteinase domain 9 antibody
  • ADAM 9 antibody
  • ADAM metallopeptidase domain 9 antibody
  • Cellular disintegrin related protein antibody
  • Cellular disintegrin related protein antibody
  • Disintegrin and metalloproteinase domain 9 antibody
  • KIAA0021 antibody
  • MCMP antibody
  • MDC9 antibody
  • MDC9 antibody
  • Meltrin gamma antibody
  • Metalloprotease disintegrin cysteine rich protein 9 antibody
  • Mltng antibody
  • Myeloma cell metalloproteinase antibody
  • Myeloma cell metalloproteinase antibody
see all

Database links

Protocols

  • Recommended WB protocol

    • References for Anti-ADAM9 antibody - Propeptide domain (ab39175)

    This product has been referenced in:

    • Yang Xet al. Secretory phospholipase A2 type III enhances alpha-secretase-dependent amyloid precursor protein processing through alterations in membrane fluidity. J Lipid Res 51:957-66 (2010). WB; Human.Read more (PubMed: 19805624) »

    See 1 publication for this product

    Publishing research using ab39175? Please let us know so that we can cite the reference in this datasheet

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"