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Products:Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> MMP
Overview
Product name
Anti-ADAM9 antibody
See all ADAM9 products (9) ...
Description
Mouse monoclonal to ADAM9
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment: QTSHLSSYEI ITPWRLTRER REAPRPYSKQ VSYVIQAEGK EHIIHLERNK DLLPEDFVVY TYNKEGTLIT DHPNIQNHCH YRGYVEGVHN SSIALSDCFG , corresponding to amino acids 36-136 of Human ADAM9
QTSHLSSYEI ITPWRLTRER REAPRPYSKQ VSYVIQAEGK EHIIHLERNK DLLPEDFVVY TYNKEGTLIT DHPNIQNHCH YRGYVEGVHN SSIALSDCFG
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG1
Light chain type
kappa
Research areas
Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Metalloprotease >> ADAMs
Cancer >> Invasion/microenvironment >> ECM >> Extracellular matrix >> ADAM protein family
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> ADAM Protein Family
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> MMP
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Western blot - ADAM9 antibody (ab57934)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab57934 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
ADAM9 encodes disintegrin and metalloprotease (ADAM) domain 9, which is a member of the ADAM protein family. Members of this family are membrane- anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell- cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The member encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
Cellular localization
Isoform 1: Cell membrane; single-pass type I membrane protein. Isoform 2: Secreted protein.
Alternative names
- A disintegrin and metalloproteinase domain 9 antibody
- ADAM 9 antibody
- ADAM metallopeptidase domain 9 antibody
see all
Database links
- Entrez Gene: 8754 Human
- Omim: 602713 Human
- SwissProt: B7ZLN7 Human
- SwissProt: Q10718 Human
- SwissProt: Q13443 Human
- Unigene: 591852 Human
Anti-ADAM9 antibody images:
Western blot - ADAM9 antibody (ab57934)
ADAM9 antibody (ab57934) at 1ug/lane + A-431 cell lysate at 25ug/lane.
References for Anti-ADAM9 antibody (ab57934)
This product has been referenced in:
- Donmez Get al. SIRT1 Suppresses beta-Amyloid Production by Activating the alpha-Secretase Gene ADAM10. Cell 142:320-332 (2010). WB; Mouse.Read more (PubMed: 20655472) »
See 1 publication for this product
Publishing research using ab57934? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"