Overview
- Product nameAnti-ADAMTS12 antibody - Catalytic domainSee all ADAMTS12 primary antibodies ...
- DescriptionRabbit polyclonal to ADAMTS12 - Catalytic domain
- Tested applicationsWB more details
- Species reactivityReacts with: Human
- Immunogen
A synthetic peptide based on the catalytic domain of human ADAMTS12.
- General notesImmunizing peptide available on request – please contact a member of staff to ask for availability
Properties
- FormLiquid
- Storage instructionsStore at -20°C. Stable for 12 months at -20°C
- Storage bufferPreservative: 0.05% Sodium Azide
Constituents: 50% Glycerol, PBS, 500mM Sodium chloride, pH 7.4 -
Concentration information loading... - PurityImmunogen affinity purified
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab59814 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: 1/1000 - 1/5000. Predicted molecular weight: 178 kDa. |
Target
- RelevanceThis protein is a disintegrin and metalloproteinase with thrombospondin motifs 12 (ADAMTS12), which is a member of the ADAMTS protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin like domain, and a thrombospondin type 1 (TS 1) motif. Individual members of this family differ in the number of C terminal TS 1 motifs, and some have unique C terminal domains. The enzyme encoded by this gene contains 8 TS 1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion.
- Cellular localizationSecreted
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Database links
- Entrez Gene: 81792 Human
- Entrez Gene: 81792 Human
- Omim: 606184 Human
- SwissProt: P58397 Human
- SwissProt: P58397 Human
- Unigene: 481865 Human
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Alternative names
- A disintegrin and metalloproteinase with thrombospondin motifs 12 antibodyA disintegrin like and metalloprotease with thrombospondin type 1 motif 12 antibodyADAM metallopeptidase with thrombospondin type 1 motif 12 antibodyADAM TS 12 antibody
References for Anti-ADAMTS12 antibody - Catalytic domain (ab59814)
ab59814 has not yet been referenced specifically in any publications.
