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Western blot - ADAMTS15 antibody - Catalytic domain (ab59826)
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Product Name
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ADAMTS15 antibody - Catalytic domain
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See all ADAMTS15 antibodies (3)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to ADAMTS15 - Catalytic domain
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Immunogen
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A synthetic peptide based on the catalytic domain of human ADAMTS15
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Reacts with
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Hu
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Specificity
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We have a range of domain specific antibodies for this target. For a full list please see all ADAMTS15 antibodies
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Tested applications
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: 1/1000 - 1/5000. Predicted molecular weight: 103 kDa.
The recommended starting concentration for Western blots is 1:1,000 when using colorimetric substrates such as BCIP/NBT, and 1:5,000 for chemiluminescent substrates.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Cancer >> Invasion/microenvironment >> ECM >> Extracellular matrix >> ADAM protein family
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> ADAM Protein Family
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Relevance
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ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.05% Sodium Azide
Constituents: 50% Glycerol, PBS, 500mM Sodium chloride, pH 7.4 Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at -20°C. Stable for 12 months at -20°C
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Notes
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Immunizing peptide available on request – please contact a member of staff to ask for availability
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ADAMTS15 antibody - Catalytic domain is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for ADAMTS15 antibody - Catalytic domain images, references, products related to ab59826 and other tools.
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ADAMTS15 antibody - Catalytic domain images:
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 Western blot - ADAMTS15 antibody - Catalytic domain (ab59826)
All lanes : ADAMTS15 antibody - Catalytic domain (ab59826) at 1/1000 dilution
Lane 1 : Whole cell lysate prepared from Madin Darby canine kidney (MDCK) cells (treated with SF)
Lane 2 : Whole cell lysate prepared from Madin Darby canine kidney (MDCK) cells (treated with TPA)
Lane 3 : Whole cell lysate prepared from Madin Darby canine kidney (MDCK) cells (treated with ILA-beta)
Lane 4 : Whole cell lysate prepared from Madin Darby canine kidney (MDCK) cells (treated with TNF-alpha)
Lysates/proteins at 30 µl per lane.
Predicted band size : 103 kDa
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Search PubMed (MEDLINE) for references to ADAMTS15
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ADAMTS15 antibody - Catalytic domain - more information
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