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Products:Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> ADAM Protein Family
Overview
Product name
Anti-ADAMTS15 antibody - Catalytic domain
See all ADAMTS15 products (3) ...
Description
Rabbit polyclonal to ADAMTS15 - Catalytic domain
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
A synthetic peptide based on the catalytic domain of human ADAMTS15
General notes
Immunizing peptide available on request – please contact a member of staff to ask for availability
Properties
Form
Liquid
Storage instructions
Store at -20°C. Stable for 12 months at -20°C
Storage buffer
Preservative: 0.05% Sodium Azide
Constituents: 50% Glycerol, PBS, 500mM Sodium chloride, pH 7.4
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Invasion/microenvironment >> ECM >> Extracellular matrix >> ADAM protein family
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> ADAM Protein Family
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Western blot - ADAMTS15 antibody - Catalytic domain (ab59826)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab59826 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes
WB: 1/1000 - 1/5000. Predicted molecular weight: 103 kDa.
The recommended starting concentration for Western blots is 1:1,000 when using colorimetric substrates such as BCIP/NBT, and 1:5,000 for chemiluminescent substrates.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration.
Cellular localization
Secreted
Alternative names
- A disintegrin and metalloproteinase with thrombospondin motifs 15 antibody
- A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 motif 15 antibody
- A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 motif 15 preproprotein antibody
see all
Database links
- Entrez Gene: 170689 Human
- Omim: 607509 Human
- SwissProt: Q32MI6 Human
- SwissProt: Q8TE58 Human
- Unigene: 534221 Human
Anti-ADAMTS15 antibody - Catalytic domain images:
Western blot - ADAMTS15 antibody - Catalytic domain (ab59826)
All lanes : Anti-ADAMTS15 antibody - Catalytic domain (ab59826) at 1/1000 dilution
Lane 1 : Whole cell lysate prepared from Madin Darby canine kidney (MDCK) cells (treated with SF)
Lane 2 : Whole cell lysate prepared from Madin Darby canine kidney (MDCK) cells (treated with TPA)
Lane 3 : Whole cell lysate prepared from Madin Darby canine kidney (MDCK) cells (treated with ILA-beta)
Lane 4 : Whole cell lysate prepared from Madin Darby canine kidney (MDCK) cells (treated with TNF-alpha)
Lysates/proteins at 30 µl per lane.
Predicted band size : 103 kDa
References for Anti-ADAMTS15 antibody - Catalytic domain (ab59826)
ab59826 has not yet been referenced specifically in any publications.
Publishing research using ab59826? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"