ADAMTSL3 protein (His-DHFR tag) (ab127140)
Our Abpromise guarantee covers the use of ab127140 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|SDS-PAGE||SDS-PAGE: Use at an assay dependent dilution.|
- A disintegrin like and metalloprotease domain with thrombospondin type I motifs like 3ADAMTS like 3ADAMTS-like protein 3
Contains 1 PLAC domain.
Contains 10 TSP type-1 domains.
modificationsGlycosylated (By similarity). Can be O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X(2)-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTS family members. Also can be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence W-X-X-W of the TPRs, and N-glycosylated. These other glycosylations can also facilitate secretion.
References for ADAMTSL3 protein (His-DHFR tag) (ab127140)
ab127140 has not yet been referenced specifically in any publications.