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ADBR2 + Gαolf fusion protein (Active) (ab90747)

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Overview

  • Product nameADBR2 + Gαolf fusion protein (Active)
  • Protein descriptionRecombinant full length Human ADBR2 (amino acids 1-413; UniProt P07550) with N terminal FLAG tag fused at the C-terminus to the N-terminus of Gαolf (UniProt P38405) via a His tag, expressed in Sf9 insect cells.
  • Expression hostBaculovirus infected sf9 cells

    • Properties

  • Purification notesMembrane suspension
  • Biological activityActivity: 7-15 pmol/mg
  • FormLiquid
  • Storage instructionsShipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.This product is an active protein and may elicit a biological response in vivo, handle with caution.
  • Storage bufferPreservative: None
    Constituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab90747 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Functional Studies
  • Application notesFuncS: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Protein info

    • Alternative names
        Adenylate cyclase-stimulating G alpha protein olfactory typeADRB2ADRB2R
        ADRBRAdrenergic beta-2- receptor surfaceB2ARBARbeta-2 adrenergic receptorBeta-2 adrenoceptorBETA2ARCatecholamine receptorGNALGuanine nucleotide binding protein (G protein) alpha activating activity polypeptide olfactory typeGuanine nucleotide-binding protein G(olf) subunit alpha
      see all
  • RelevanceADBR2 is a member of the G protein-coupled receptor superfamily. It is activated by the catecholamine epinephrine and couples to the G protein Gs to mediate adenylate cyclase activation. ADBR2 receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. Gaolf mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. It may be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters.
  • Cellular localizationADBR2: Cell membrane; Multi-pass membrane protein.

    • References for ADBR2 + Gαolf fusion protein (Active) (ab90747)

    ab90747 has not yet been referenced specifically in any publications.

    Publishing research using ab90747 ? Please let us know so that we can cite the reference in this datasheet

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