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Anti-ADCY3 antibody (ab14778)

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Overview

Product name

Anti-ADCY3 antibody
See all ADCY3 products (3) ...

Description

Rabbit polyclonal to ADCY3

Tested applications

IP, WBmore details

Cross reactivity

Reacts with

Mouse, Rat, Dog, Human

Immunogen

The antibodies were generated against a synthetic peptide sequence (unfortunately, the amino acid sequence is considered to be commercially sensitive) unique to PAC3 protein. All peptides were amidated before conjugation.

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.02% Sodium Azide

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Purification notes

The antibodies are affinity purified against immobilized antigen based affinity chromatography which yielded epitope-specific antibodies.

Clonality

Polyclonal

Isotype

IgG

Research areas

Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Integration of energy metabolism
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> GPCR

Applications

Show applications key

Our Abpromise guarantee covers the use of ab14778 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

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    IP

      See more...Read more →

    IP: Use at an assay dependent dilution. (Use 5 ul for 2 x 107 cells.)

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    WB

     WB: 1/500Detects a band ...Read more →

    WB: 1/500Detects a band of approximately 119 kDa (predicted molecular weight: 129 kDa).

Target

Function

Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration.

Tissue specificity

Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle.

Sequence similarities

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Contains 2 guanylate cyclase domains.

Cellular localization

Membrane.

Target information above from: UniProt accessionO60266 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • olfactive type antibody
  • AC-III antibody
  • AC3 antibody
  • ADCY3 antibody
  • ADCY3_HUMAN antibody
  • adenylate cyclase 3 antibody
  • Adenylate cyclase antibody
  • Adenylate cyclase type 3 antibody
  • Adenylate cyclase type III antibody
  • Adenylyl cyclase 3 antibody
  • ATP pyrophosphate lyase antibody
  • ATP pyrophosphate-lyase 3 antibody
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Database links

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References for Anti-ADCY3 antibody (ab14778)

This product has been referenced in:

  • Gonzalez-Iglesias AEet al. Dependence of electrical activity and calcium influx-controlled prolactin release on adenylyl cyclase signaling pathway in pituitary lactotrophs. Mol Endocrinol 20:2231-46 (2006).Read more (PubMed: 16645040) »

See 1 publication for this product

Publishing research using ab14778? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"