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Products:Cardiovascular >> Hypoxia >> Hypoxia-Regulated
Overview
Product name
Anti-ADFP antibody
See all ADFP products (6) ...
Description
Rabbit polyclonal to ADFP
Tested applications
ICC/IF, WBmore details
Cross reactivity
Reacts with
Mouse, Human, Rhesus monkey
Predicted to work with
Rat
Immunogen
A synthetic peptide made to a C-terminal region within residues 350-425 of the mouse ADFP protein.
Positive control
Mouse and human liver lysate
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 30% Glycerol, PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Cardiovascular >> Atherosclerosis >> Lipid transport
Signal Transduction >> Metabolism >> Lipid metabolism
Cardiovascular >> Lipids / Lipoproteins >> Adipose Related >> Lipid Droplet Protein
Cardiovascular >> Hypoxia >> Hypoxia-Regulated
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Western blot - ADFP antibody (ab52356)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab52356 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ICC/IF: Use at an assay dependent dilution. (PubMed: 20335253)
WB: Use a concentration of 2 µg/mlDetects a band of approximately 48 kDa (predicted molecular weight: 48 kDa).
Target
Function
May be involved in development and maintenance of adipose tissue.
Tissue specificity
Milk lipid globules.
Sequence similarities
Belongs to the perilipin family.
Post-translational
modifications
Acylated; primarily with C14, C16 and C18 fatty acids.
Cellular localization
Membrane.
Target information above from: UniProt accessionQ99541
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- ADFP antibody
- Adipophilin antibody
- Adipose differentiation related protein antibody
see all
Database links
- Entrez Gene: 123 Human
- Entrez Gene: 11520 Mouse
- Entrez Gene: 298199 Rat
- Omim: 103195 Human
- SwissProt: Q99541 Human
- SwissProt: P43883 Mouse
- Unigene: 3416 Human
- Unigene: 381 Mouse
Anti-ADFP antibody images:
Western blot - ADFP antibody (ab52356)
Anti-ADFP antibody (ab52356) at 2 µg/ml + mouse liver lysate
Predicted band size : 48 kDa
Observed band size : 48 kDa
References for Anti-ADFP antibody (ab52356)
This product has been referenced in:
- Becker Let al. A macrophage sterol-responsive network linked to atherogenesis. Cell Metab 11:125-35 (2010). WB; Mouse.Read more (PubMed: 20142100) »
- Cheung Wet al. Rotaviruses associate with cellular lipid droplet components to replicate in viroplasms, and compounds disrupting or blocking lipid droplets inhibit viroplasm formation and viral replication. J Virol 84:6782-98 (2010). ICC/IF; Rhesus monkey.Read more (PubMed: 20335253) »
See all 2 publications for this product
Publishing research using ab52356? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"