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Products:Signal Transduction >> Metabolism >> Amino Acids
Overview
Product name
Anti-ADI1 antibody
See all ADI1 products (2) ...
Description
Chicken polyclonal to ADI1
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Full length native protein (purified), corresponding to amino acids 1-179 of Human ADI1.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgY
Research areas
Cancer >> Tumor biomarkers >> Other
Signal Transduction >> Metabolism >> Amino Acids
Applications
Show applications key
Our Abpromise guarantee covers the use of ab37877 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at an assay dependent dilution. Predicted molecular weight: 21 kDa.
Target
Function
Has aci-reductone dioxygenase (ARD) activity and can function in the 5-methylthioadenosine (MTA) methionine salvage pathway. Down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.
Tissue specificity
Detected in heart, colon, lung, stomach, brain, spleen, liver, skeletal muscle and kidney.
Pathway
Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6.
Sequence similarities
Belongs to the acireductone dioxygenase (ARD) family.
Cellular localization
Cell membrane. Nucleus.
Target information above from: UniProt accessionQ9BV57
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 1 antibody
- 2-dihydroxy-3-keto-5-methylthiopentene dioxygenase antibody
- Aci reductone dioxygenase antibody
see all
Database links
- Entrez Gene: 55256 Human
- NCBI: NP_060739.1 Human
- SwissProt: Q9BV57 Human
- Unigene: 502773 Human
References for Anti-ADI1 antibody (ab37877)
ab37877 has not yet been referenced specifically in any publications.
Publishing research using ab37877? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"