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Overview

  • Product nameAF-DX 116 (Otenzepad)
  • Description
    M2 antagonist
  • Alternative names
    Otenzepad
  • Biological descriptionSelective M2 receptor antagonist.
  • Purity> 99%

    • Properties

  • Chemical name11-[[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
  • Molecular Weight421.54
  • Chemical structureChemical Structure
  • Molecular formulaC24H31N5O2
  • CAS Number102394-31-0
  • PubChem identifier107867
  • Storage instructionsStore at room temperature.
  • Solubility overviewSoluble in DMSO to 25 mM
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  • SMILESO=C(CN1CCCCC1CN(CC)CC)N4c2ccccc2C(=O)Nc3cccnc34
  • Source

    Synthetic

  • Research Areas

    • References for AF-DX 116 (Otenzepad) (ab120152)

    This product has been referenced in:
    • Micheletti R  et al. AF-DX 116, a cardioselective muscarinic antagonist. J Pharmacol Exp Ther 241:628-34 (1987). Read more (PubMed: 2883303) »
    • Giraldo E  et al. Distribution of muscarinic receptor subtypes in rat brain as determined in binding studies with AF-DX 116 and pirenzepine. Life Sci 40:833-40 (1987). Read more (PubMed: 3821380) »
    • Hammer R  et al. Binding profile of a novel cardioselective muscarine receptor antagonist, AF-DX 116, to membranes of peripheral tissues and brain in the rat. Life Sci 38:1653-62 (1986). Read more (PubMed: 3754610) »

    See all 2 Publications for this product

    Publishing research using ab120152 ? Please let us know so that we can cite the reference in this datasheet

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"