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Anti-AF4 antibody (ab31812)

This fast track antibody is not yet fully characterised. It is subject to these terms and conditions

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Overview

Product name

Anti-AF4 antibody
See all AF4 products (2) ...

Description

Rabbit polyclonal to AF4

This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

Cross reactivity

Predicted to work with

Human

Immunogen

Synthetic peptide conjugated to KLH derived from within residues 500 - 600 of Human AF4.

Read Abcam's proprietary immunogen policy

(Peptide available as ab32738.)

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Cancer >> Oncoproteins/suppressors >> Oncoproteins >> Transcription factors
Epigenetics and Nuclear Signaling >> Transcription >> Cancer susceptibility >> Proto-oncogenes

Applications

Application notes


This antibody gave a positive result in ELISA against the immunizing peptide (ab32738).
Not yet tested in other applications.

Target

Involvement in disease

Note=A chromosomal aberration involving AFF1 is associated with acute leukemias. Translocation t(4;11)(q21;q23) with MLL/HRX. The result is a rogue activator protein.

Sequence similarities

Belongs to the AF4 family.

Cellular localization

Nucleus.

Target information above from: UniProt accessionP51825 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • AF 4 antibody
  • AF 4 protein antibody
  • AF-4 protein antibody
  • AF4-MLL antibody
  • AF4/FMR2 family member 1 antibody
  • AFF 1 antibody
  • AFF1 antibody
  • AFF1_HUMAN antibody
  • ALL1 fused gene from chromosome 4 antibody
  • ALL1-fused gene from chromosome 4 protein antibody
  • FEL antibody
  • MGC134969 antibody
  • MLL/AF4 antibody
  • MLLT2 antibody
  • MYELOID/LYMPHOID OR MIXED LINEAGE LEUKEMIA TRANSLOCATED TO 2; MLLT2 antibody
  • PBM1 antibody
  • Protein AF-4 antibody
  • Protein FEL antibody
  • Proto-oncogene AF4 antibody
see all

Database links

References for Anti-AF4 antibody (ab31812)

ab31812 has not yet been referenced specifically in any publications.

Publishing research using ab31812? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"