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Products:Epigenetics and Nuclear Signaling >> Transcription >> Cancer susceptibility >> Proto-oncogenes
Overview
Product name
AF4 peptide
See all AF4 products (2) ...
Protein description
Synthetic peptide derived from within residues 500 - 600 of Human AF4.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab31812 - AF4 antibody.
Protein length
1210 amino acids
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Information available upon request.
Concentration
Concentration information loading...
Research areas
Cancer >> Oncoproteins/suppressors >> Oncoproteins >> Transcription factors
Epigenetics and Nuclear Signaling >> Transcription >> Cancer susceptibility >> Proto-oncogenes
Applications
Application notes
This peptide can be used with studies using ab31812.
Protein info
Involvement in disease
Note=A chromosomal aberration involving AFF1 is associated with acute leukemias. Translocation t(4;11)(q21;q23) with MLL/HRX. The result is a rogue activator protein.
Sequence similarities
Belongs to the AF4 family.
Cellular localization
Nucleus.
Target information above from: UniProt accessionP51825
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for AF4 peptide (ab32738)
ab32738 has not yet been referenced specifically in any publications.
Publishing research using ab32738? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"