Overview

  • Product name
    AG 1478
  • Description
    Selective EGF receptor tyrosine kinase inhibitor
  • Biological description
    Selective EGF receptor tyrosine kinase inhibitor (Ki = 10 nM). Supresses proliferation and cell-cycle progression. Cell-permeable and active in vivo.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Shushan A  et al. The AG1478 tyrosine kinase inhibitor is an effective suppressor of leiomyoma cell growth. Hum Reprod 19:1957-67 (2004). Read more (PubMed: 15205403) »
  • Zhu XF  et al. EGFR tyrosine kinase inhibitor AG1478 inhibits cell proliferation and arrests cell cycle in nasopharyngeal carcinoma cells. Cancer Lett 169:27-32 (2001). Read more (PubMed: 11410322) »
  • Osherov N & Levitzki A Epidermal-growth-factor-dependent activation of the src-family kinases. Eur J Biochem 225:1047-53 (1994). Read more (PubMed: 7525285) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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