Overview

  • Product name
  • Description
    Rabbit polyclonal to AGL
  • Host species
    Rabbit
  • Specificity
    Detects endogenous levels of total AGL protein.
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human AGL aa 1519-1531 (internal sequence).
    Database link: P35573

  • Positive control
    • Human thyroid cancer tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab198713 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/25 - 1/100.

Target

  • Function
    Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.
  • Tissue specificity
    Liver, kidney and lymphoblastoid cells express predominantly isoform 1; whereas muscle and heart express not only isoform 1, but also muscle-specific isoform mRNAs (isoforms 2, 3 and 4). Isoforms 5 and 6 are present in both liver and muscle.
  • Involvement in disease
    Glycogen storage disease 3
  • Sequence similarities
    Belongs to the glycogen debranching enzyme family.
  • Post-translational
    modifications
    The N-terminus is blocked.
    Ubiquitinated.
  • Cellular localization
    Cytoplasm. Under glycogenolytic conditions localizes to the nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1110061O17Rik antibody
    • 4-1 antibody
    • 4-glucantransferase antibody
    • 6-glucosidase antibody
    • 9430004C13Rik antibody
    • 9630046L06Rik antibody
    • AGL antibody
    • AI850929 antibody
    • Amylo 1 6 glucosidase 4 alpha glucanotransferase antibody
    • Amylo-1 antibody
    • Amylo-alpha-1 antibody
    • C77197 antibody
    • Dextrin 6-alpha-D-glucosidase antibody
    • GDE antibody
    • GDE_HUMAN antibody
    • Glycogen debrancher antibody
    • Glycogen debranching enzyme antibody
    • Glycogen storage disease type III antibody
    • Oligo-1 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue labeling AGL with ab198713 at 1/30 dilution.

References

ab198713 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab198713.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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