Overview

  • Product nameAnti-AIPL1 antibodySee all AIPL1 primary antibodies ...
  • Description
    Rabbit polyclonal to AIPL1
  • Tested applicationsWB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Recombinant fragment, corresponding to amino acids 57-320 of Human AIPL1 (BC012055).

  • Positive control
    • Mouse brain and Human fetal heart lysates; Human fetal heart tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab108538 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/2000. Predicted molecular weight: 44 kDa.
ELISA 1/20000 - 1/80000.
IHC-P 1/100 - 1/500.

Target

  • FunctionMay be important in protein trafficking and/or protein folding and stabilization.
  • Tissue specificityHighly expressed in retina. Specifically localized to the developing photoreceptor layer and within the photoreceptors of the adult retina.
  • Involvement in diseaseDefects in AIPL1 are the cause of Leber congenital amaurosis type 4 (LCA4) [MIM:604393]. LCA designates a clinically and genetically heterogeneous group of childhood retinal degenerations, generally inherited in an autosomal recessive manner. Affected infants have little or no retinal photoreceptor function as tested by electroretinography. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
  • Sequence similaritiesContains 1 PPIase FKBP-type domain.
    Contains 3 TPR repeats.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • A930007I01Rik antibody
    • Aipl1 antibody
    • AIPL1_HUMAN antibody
    • AIPL2 antibody
    • Aryl hydrocarbon interacting protein like 1 antibody
    • Aryl hydrocarbon receptor interacting protein like 1 antibody
    • Aryl-hydrocarbon-interacting protein-like 1 antibody
    • LCA4 antibody
    • MGC25485 antibody
    • OTTHUMP00000128207 antibody
    • OTTMUSP00000006382 antibody
    • RP23-401C17.1 antibody
    see all

Anti-AIPL1 antibody images

  • All lanes : Anti-AIPL1 antibody (ab108538) at 1/1000 dilution

    Lane 1 : Mouse brain lysate
    Lane 2 : Human fetal heart lysate


    Predicted band size : 44 kDa
  • ab108538, at 1/100 dilution, staining AIPL1 in formalin-fixed, paraffin-embedded Human fetal heart by Immunohistochemistry.

References for Anti-AIPL1 antibody (ab108538)

ab108538 has not yet been referenced specifically in any publications.

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