You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Overview

  • Product nameAnti-AIPL1 antibodySee all AIPL1 primary antibodies ...
  • Description
    Rabbit polyclonal to AIPL1
  • Tested applicationsWB, ELISA, ICC/IF more details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    A 17 amino acid synthetic peptide near the carboxy terminus of human AIPL1 (NP_055151).

  • Positive controlHuman brain tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab79039 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 44 kDa.
ELISA ELISA: Use at an assay dependent dilution.
ICC/IF ICC/IF: Use a concentration of 20 µg/ml.

Target

  • FunctionMay be important in protein trafficking and/or protein folding and stabilization.
  • Tissue specificityHighly expressed in retina. Specifically localized to the developing photoreceptor layer and within the photoreceptors of the adult retina.
  • Involvement in diseaseDefects in AIPL1 are the cause of Leber congenital amaurosis type 4 (LCA4) [MIM:604393]. LCA designates a clinically and genetically heterogeneous group of childhood retinal degenerations, generally inherited in an autosomal recessive manner. Affected infants have little or no retinal photoreceptor function as tested by electroretinography. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
  • Sequence similaritiesContains 1 PPIase FKBP-type domain.
    Contains 3 TPR repeats.
  • Cellular localizationCytoplasm. Nucleus.

    • Target information above from: UniProt accession Q9NZN9 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        A930007I01Rik antibodyAipl1 antibodyAIPL1_HUMAN antibody
        AIPL2 antibodyAryl hydrocarbon interacting protein like 1 antibodyAryl hydrocarbon receptor interacting protein like 1 antibodyAryl-hydrocarbon-interacting protein-like 1 antibodyLCA4 antibodyMGC25485 antibodyOTTHUMP00000128207 antibodyOTTMUSP00000006382 antibodyRP23-401C17.1 antibody
      see all

    Anti-AIPL1 antibody images

    • Western blot - AIPL1 antibody (ab79039)
      Western blot - AIPL1 antibody (ab79039)
      Lane 1 : Anti-AIPL1 antibody (ab79039) at 1 µg/ml
      Lane 2 : Anti-AIPL1 antibody (ab79039) at 2 µg/ml

      Lane 1 : Human brain tissue lysate
      Lane 2 : Human brain tissue lysate

      Lysates/proteins at 15 µg per lane.


      Predicted band size : 44 kDa
      Observed band size : 36 kDa (why is the actual band size different from the predicted?)

    References for Anti-AIPL1 antibody (ab79039)

    ab79039 has not yet been referenced specifically in any publications.

    Publishing research using ab79039 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab79039 Submit a Question for ab79039

    There are currently no Abreviews or Questions for ab79039.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"