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Products:Signal Transduction >> Metabolism >> Energy Metabolism
Overview
Product name
Anti-AKR1B10 antibody
See all AKR1B10 products (7) ...
Description
Mouse monoclonal to AKR1B10
Tested applications
WB, IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment: VSKLWPTFFE RPLVRKAFEK TLKDLKLSYL DVYLIHWPQG FKSGDDLFPK DDKGNAIGGK ATFLDAWE, corresponding to amino acids 76-144 of Human AKR1B10
VSKLWPTFFE RPLVRKAFEK TLKDLKLSYL DVYLIHWPQG FKSGDDLFPK DDKGNAIGGK ATFLDAWE
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2a
Light chain type
kappa
Research areas
Cancer >> Tumor biomarkers >> Enzymes >> Other
Signal Transduction >> Metabolism >> Drug metabolism
Signal Transduction >> Metabolism >> Energy Metabolism
Applications
Show applications key
Our Abpromise guarantee covers the use of ab57547 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
IHC-P: Use at a concentration of 3 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
Tissue specificity
Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.
Sequence similarities
Belongs to the aldo/keto reductase family.
Cellular localization
Cytoplasm.
Target information above from: UniProt accessionO60218
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Aldose reductase like antibody
- Aldose reductase related protein antibody
- ARL 1 antibody
see all
Database links
- Entrez Gene: 57016 Human
- Omim: 604707 Human
- SwissProt: O60218 Human
- Unigene: 116724 Human
Anti-AKR1B10 antibody images:
IHC-P - AKR1B10 antibody (ab57547)
AKR1B10 antibody (ab57547) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human colon.
Western blot - AKR1B10 antibody (ab57547)
AKR1B10 antibody (ab57547) at 1ug/lane + HepG2 cell lysate at 25ug/lane.
References for Anti-AKR1B10 antibody (ab57547)
ab57547 has not yet been referenced specifically in any publications.
Publishing research using ab57547? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"