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Anti-AKR1B10 antibody (ab57547)

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Overview

Product name

Anti-AKR1B10 antibody
See all AKR1B10 products (7) ...

Description

Mouse monoclonal to AKR1B10

Tested applications

WB, IHC-Pmore details

Cross reactivity

Reacts with

Human

Immunogen

Recombinant fragment: VSKLWPTFFE RPLVRKAFEK TLKDLKLSYL DVYLIHWPQG FKSGDDLFPK DDKGNAIGGK ATFLDAWE, corresponding to amino acids 76-144 of Human AKR1B10

VSKLWPTFFE RPLVRKAFEK TLKDLKLSYL DVYLIHWPQG FKSGDDLFPK DDKGNAIGGK ATFLDAWE

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
PBS, pH 7.2

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Isotype

IgG2a

Light chain type

kappa

  • IHC-P - AKR1B10 antibody (ab57547)IHC-P - AKR1B10 antibody (ab57547) image (enlarge)

  • Western blot - AKR1B10 antibody (ab57547)Western blot - AKR1B10 antibody (ab57547) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab57547 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

WB: Use at a concentration of 1-5 µg/ml.
IHC-P: Use at a concentration of 3 µg/ml.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Function

Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.

Tissue specificity

Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.

Sequence similarities

Belongs to the aldo/keto reductase family.

Cellular localization

Cytoplasm.

Target information above from: UniProt accessionO60218 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Aldose reductase like antibody
  • Aldose reductase related protein antibody
  • ARL 1 antibody
  • hARP antibody
  • SI reductase antibody
  • Small intestine reductase antibody
  • AK1BA_HUMAN antibody
  • AKR1B10 antibody
  • AKR1B11 antibody
  • AKR1B12 antibody
  • Aldo keto reductase family 1 member B10 antibody
  • aldo keto reductase family 1 member B11 antibody
  • Aldo-keto reductase family 1 member B10 antibody
  • aldose reductase like 1 antibody
  • aldose reductase like peptide antibody
  • Aldose reductase-like antibody
  • Aldose reductase-related protein antibody
  • ALDRLn antibody
  • ARL-1 antibody
  • ARL1 antibody
  • ARP antibody
  • hARP antibody
  • HIS antibody
  • HSI antibody
  • SI reductase antibody
  • Small intestine reductase antibody
see all

Anti-AKR1B10 antibody images:

  IHC-P - AKR1B10 antibody (ab57547)

IHC-P - AKR1B10 antibody (ab57547)

AKR1B10 antibody (ab57547) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human colon.

  Western blot - AKR1B10 antibody (ab57547)

Western blot - AKR1B10 antibody (ab57547)

AKR1B10 antibody (ab57547) at 1ug/lane + HepG2 cell lysate at 25ug/lane.

References for Anti-AKR1B10 antibody (ab57547)

ab57547 has not yet been referenced specifically in any publications.

Publishing research using ab57547? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"