Anti-AKR1B10 antibody (ab62218)

Overview

• Product nameAnti-AKR1B10 antibodySee all AKR1B10 primary antibodies ...
• Description
  Rabbit polyclonal to AKR1B10
• Tested applicationsELISA, WB more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse, Rat, Cow, Fruit fly (Drosophila melanogaster), Zebrafish
• Immunogen

  Synthetic peptide corresponding to a sequence within N terminal amino acids 37-86 of Human AKR1B10. (DAGYRHIDCA YVYQNEHEVG EAIQEKIQEK AVKREDLFIV SKLWPTFFER)

  Run BLAST with Run BLAST with
• Positive controlA549 cells

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: 2% Sucrose, PBS
• Concentration information loading...
• PurityProtein A purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Drug metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Energy transfer pathways
  • Energy Metabolism

  • Cancer
  • Tumor biomarkers
  • Enzymes
  • Other

  • Signal Transduction
  • Metabolism
  • Drug metabolism

  • Signal Transduction
  • Metabolism
  • Energy Metabolism

Applications

Target

• FunctionActs as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
• Tissue specificityFound in many tissues. Highly expressed in small intestine, colon and adrenal gland.
• Sequence similaritiesBelongs to the aldo/keto reductase family.
• Cellular localizationLysosome. Secreted. Secreted through a lysosome-mediated non-classical pathway.

Target information above from: UniProt accession O60218 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 57016 Human
  • Entrez Gene: 67861 Mouse
  • Entrez Gene: 296972 Rat
  • Omim: 604707 Human
  • SwissProt: O60218 Human
  • Unigene: 116724 Human
  • Unigene: 70371 Mouse
  • Unigene: 228771 Rat

• Alternative names
  AK1BA_HUMAN antibodyAKR1B10 antibodyAKR1B11 antibody

  AKR1B12 antibodyAldo keto reductase family 1 member B10 antibodyaldo keto reductase family 1 member B11 antibodyAldo-keto reductase family 1 member B10 (aldose reductase) antibodyAldo-keto reductase family 1 member B10 antibodyAldo-keto reductase family 1 member B11 (aldose reductase-like) antibodyaldose reductase like 1 antibodyAldose reductase like antibodyaldose reductase like peptide antibodyAldose reductase related protein antibodyAldose reductase-like antibodyAldose reductase-related protein antibodyALDRLn antibodyARL 1 antibodyARL-1 antibodyARL1 antibodyARL1 Human small intestine reductase antibodyARP antibodyhARP antibodyHIS antibodyHSI antibodySI reductase antibodySmall intestine reductase antibody

  see all

Anti-AKR1B10 antibody images

• 

  Western blot - AKR1B10 antibody (ab62218)
  Anti-AKR1B10 antibody (ab62218) at 1.25 µg/ml + A549 cell lysate at 10 µg
  
  Secondary
  HRP conjugated anti-Rabbit IgG at 1/50000 dilution
  
  Predicted band size : 35 kDa
  Observed band size : 35 kDa