Overview

  • Product nameAnti-AKR1B10 antibodySee all AKR1B10 primary antibodies ...
  • Description
    Rabbit polyclonal to AKR1B10
  • Tested applicationsELISA, WB more details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Cow, Dog, Saccharomyces cerevisiae, Fruit fly (Drosophila melanogaster), Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a sequence within N terminal amino acids 37-86 of Human AKR1B10. (DAGYRHIDCA YVYQNEHEVG EAIQEKIQEK AVKREDLFIV SKLWPTFFER)

  • Positive control
    • A549 cells

Properties

Applications

Our Abpromise guarantee covers the use of ab62218 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
ELISA Use at an assay dependent concentration.

Titre using peptide based assay: 1:1562500.

WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 35 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionActs as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
  • Tissue specificityFound in many tissues. Highly expressed in small intestine, colon and adrenal gland.
  • Sequence similaritiesBelongs to the aldo/keto reductase family.
  • Cellular localizationLysosome. Secreted. Secreted through a lysosome-mediated non-classical pathway.
  • Target information above from: UniProt accession O60218 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
  • Alternative names
    • AK1BA_HUMAN antibody
    • AKR1B10 antibody
    • AKR1B11 antibody
    • AKR1B12 antibody
    • Aldo keto reductase family 1 member B10 antibody
    • aldo keto reductase family 1 member B11 antibody
    • Aldo-keto reductase family 1 member B10 (aldose reductase) antibody
    • Aldo-keto reductase family 1 member B10 antibody
    • Aldo-keto reductase family 1 member B11 (aldose reductase-like) antibody
    • aldose reductase like 1 antibody
    • Aldose reductase like antibody
    • aldose reductase like peptide antibody
    • Aldose reductase related protein antibody
    • Aldose reductase-like antibody
    • Aldose reductase-related protein antibody
    • ALDRLn antibody
    • ARL 1 antibody
    • ARL-1 antibody
    • ARL1 antibody
    • ARL1 Human small intestine reductase antibody
    • ARP antibody
    • hARP antibody
    • HIS antibody
    • HSI antibody
    • SI reductase antibody
    • Small intestine reductase antibody
    see all

Anti-AKR1B10 antibody images

  • Anti-AKR1B10 antibody (ab62218) at 1.25 µg/ml + A549 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 35 kDa
    Observed band size : 35 kDa

References for Anti-AKR1B10 antibody (ab62218)

ab62218 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab62218.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"