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AKR1B10 protein (Human) (ab85415)

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Overview

Product name

AKR1B10 protein (Human)
See all AKR1B10 products (3) ...

Protein description

Recombinant full length Human AKR1B10; amino acids 1-316, 36kDa. Swiss ID = O60218.

Expression host

E. coli

Properties

Purity

>95% by SDS-PAGE

Purification notes

ab85415 is purified using conventional chromatography techniques.

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 10% Glycerol, 20mM Tris HCl, pH 8.0

Concentration

Concentration information loading...

Sequence notes

MATFVELSTK AKMPIVGLGT WKSPLGKVKE AVKVAIDAGY RHIDCAYVYQ NEHEVGEAIQ EKIQEKAVKR EDLFIVSKLW PTFFERPLVR KAFEKTLKDL KLSYLDVYLI HWPQGFKSGD DLFPKDDKGN AIGGKATFLD AWEAMEELVD EGLVKALGVS NFSHFQIEKL LNKPGLKYKP VTNQVECHPY LTQEKLIQYC HSKGITVTAY SPLGSPDRPW AKPEDPSLLE DPKIKEIAAK HKKTAAQVLI RFHIQRNVIV IPKSVTPARI VENIQVFDFK LSDEEMATIL SFNRNWRACN VLQSSHLEDY PFDAEY

Research areas

Cancer >> Tumor biomarkers >> Enzymes >> Other
Signal Transduction >> Metabolism >> Drug metabolism
Signal Transduction >> Metabolism >> Energy Metabolism

  • SDS-PAGE - AKR1B10 protein (Human) (ab85415)SDS-PAGE - AKR1B10 protein (Human) (ab85415) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab85415 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Protein info

Function

Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.

Tissue specificity

Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.

Sequence similarities

Belongs to the aldo/keto reductase family.

Cellular localization

Cytoplasm.

Target information above from: UniProt accessionO60218 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

AKR1B10 protein (Human) images:

  SDS-PAGE - AKR1B10 protein (Human) (ab85415)

SDS-PAGE - AKR1B10 protein (Human) (ab85415)

15% SDS-PAGE showing ab85415 at approximately 36kDa (3µg).

References for AKR1B10 protein (Human) (ab85415)

ab85415 has not yet been referenced specifically in any publications.

Publishing research using ab85415? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"