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Anti-AKR1C2 antibody (ab54807)

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Overview

Product name

Anti-AKR1C2 antibody
See all AKR1C2 products (3) ...

Description

Mouse monoclonal to AKR1C2

Tested applications

WBmore details

Cross reactivity

Reacts with

Recombinant Fragment

Predicted to work with

Human

Immunogen

Recombinant fragment: EEPWVDPNSP VLLEDPVLCA LAKKHKRTPA LIALRYQLQR GVVVLAKSYN EQRIRQNVQV FEFQLTSEEM KAIDGLNRNV RYLTLDIFAG PPNYPFSDEY , corresponding to amino acids 224-324 of Human AKR1C2

EEPWVDPNSP VLLEDPVLCA LAKKHKRTPA LIALRYQLQR GVVVLAKSYN EQRIRQNVQV FEFQLTSEEM KAIDGLNRNV RYLTLDIFAG PPNYPFSDEY

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
PBS, pH 7.2

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Isotype

IgG2a

Light chain type

kappa

  • Western blot - AKR1C2 antibody (ab54807)Western blot - AKR1C2 antibody (ab54807) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab54807 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

WB: Use at a concentration of 1-5 µg/ml.

This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Function

Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.

Sequence similarities

Belongs to the aldo/keto reductase family.

Cellular localization

Cytoplasm.

Target information above from: UniProt accessionP52895 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • 2-dihydrobenzene-1 antibody
  • 2-diol dehydrogenase antibody
  • 3 alpha HSD3 antibody
  • 3 alpha hydroxysteroid dehydrogenase type III antibody
  • 3-alpha-HSD3 antibody
  • AK1C2_HUMAN antibody
  • AKR1C pseudo antibody
  • AKR1C2 antibody
  • Aldo keto reductase family 1 member C2 antibody
  • Aldo-keto reductase family 1 member C2 antibody
  • BABP antibody
  • Bile acid binding protein antibody
  • Chlordecone reductase homolog antibody
  • Chlordecone reductase homolog HAKRD antibody
  • DD antibody
  • DD-2 antibody
  • DD/BABP antibody
  • DD2 antibody
  • DDH 2 antibody
  • DDH2 antibody
  • Dihydrodiol dehydrogenase 2 antibody
  • Dihydrodiol dehydrogenase/bile acid binding protein antibody
  • Dihydrodiol dehydrogenase/bile acid-binding protein antibody
  • HAKRD antibody
  • HBAB antibody
  • MCDR 2 antibody
  • MCDR2 antibody
  • OTTHUMP00000044759 antibody
  • Pseudo chlordecone reductase antibody
  • Trans 1 2 dihydrobenzene 1 2 diol dehydrogenase antibody
  • Trans-1 antibody
  • Type II dihydrodiol dehydrogenase antibody
  • Type III 3 alpha hydroxysteroid dehydrogenase antibody
  • Type III 3-alpha-hydroxysteroid dehydrogenase antibody
see all

Anti-AKR1C2 antibody images:

  Western blot - AKR1C2 antibody (ab54807)

Western blot - AKR1C2 antibody (ab54807)

Western blot against tagged recombinant protein immunogen using ab54807 AKR1C2 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa.

This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

References for Anti-AKR1C2 antibody (ab54807)

ab54807 has not yet been referenced specifically in any publications.

Publishing research using ab54807? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"