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Products:Signal Transduction >> Growth Factors/Hormones >> Hormones
Overview
Product name
Anti-AKR1C2 antibody
See all AKR1C2 products (3) ...
Description
Mouse polyclonal to AKR1C2
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length Human AKR1C2 (AAH07024.1)
Positive control
Human liver lysate and transfected 293T cell lysate
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 1X PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Tumor biomarkers >> Enzymes >> Other
Signal Transduction >> Metabolism >> Drug metabolism
Signal Transduction >> Metabolism >> Energy Metabolism
Signal Transduction >> Growth Factors/Hormones >> Hormones
Applications
Show applications key
Our Abpromise guarantee covers the use of ab88312 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 µg/mlPredicted molecular weight: 37 kDa.
Target
Function
Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.
Sequence similarities
Belongs to the aldo/keto reductase family.
Cellular localization
Cytoplasm.
Target information above from: UniProt accessionP52895
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 2-dihydrobenzene-1 antibody
- 2-diol dehydrogenase antibody
- 3 alpha HSD3 antibody
see all
Database links
- Entrez Gene: 1646 Human
- Omim: 600450 Human
- SwissProt: P52895 Human
- Unigene: 460260 Human
- Unigene: 567256 Human
Anti-AKR1C2 antibody images:
Western blot - AKR1C2 antibody (ab88312)
All lanes : Anti-AKR1C2 antibody (ab88312) at 1 µg/ml
Lane 1 : transfected 293T cell lysate
Lane 2 : untransfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
goat anti-mouse IgG at 1/5000 dilution
Predicted band size : 37 kDa
Western blot - AKR1C2 antibody (ab88312)
Anti-AKR1C2 antibody (ab88312) at 1 µg/ml + human liver lysate at 25 µg
Secondary
goat anti-mouse IgG at 1/5000 dilution
Predicted band size : 37 kDa
References for Anti-AKR1C2 antibody (ab88312)
ab88312 has not yet been referenced specifically in any publications.
Publishing research using ab88312? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"