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Overview

  • Product nameAKR1C2 proteinSee all AKR1C2 proteins and peptides ...
  • Protein descriptionRecombinant full length Human AKR1C2 (amino acids 1-323) with N terminal proprietary tag, MW: 61.53 kDa inclusive of tag. P52895, AAH07024.
  • Uniprot accessionP52895
  • Molecular weight61.530kDa inclusive of tags
  • Protein length323 amino acids
  • Expression hostWheat germ

    • Properties

  • E.C. Number1--
  • FormLiquid
  • Storage instructionsShipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
  • Storage bufferpH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl
  • Concentration information loading...
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Sequence notesMDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKL AIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIF YTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLA KSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQR KLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQN VQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab114784 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    WB WB: Use at an assay dependent concentration.
    SDS-PAGE SDS-PAGE: Use at an assay dependent concentration.
    ELISA ELISA: Use at an assay dependent concentration.

    Protein info

    • Alternative names
        2-dihydrobenzene-12-diol dehydrogenase3 alpha HSD3
        3 alpha hydroxysteroid dehydrogenase type III3-alpha-HSD3AK1C2_HUMANAKR1C pseudoAKR1C2Aldo keto reductase family 1 member C2Aldo-keto reductase family 1 member C2BABPBile acid binding proteinChlordecone reductase homologChlordecone reductase homolog HAKRDDDDD-2DD/BABPDD2DDH 2DDH2Dihydrodiol dehydrogenase 2Dihydrodiol dehydrogenase/bile acid binding proteinDihydrodiol dehydrogenase/bile acid-binding proteinFLJ53800HAKRDHBABMCDR 2MCDR2OTTHUMP00000044759Pseudo chlordecone reductaseSRXY8Trans 1 2 dihydrobenzene 1 2 diol dehydrogenaseTrans-1Type II dihydrodiol dehydrogenaseType III 3 alpha hydroxysteroid dehydrogenaseType III 3-alpha-hydroxysteroid dehydrogenase
      see all
  • FunctionWorks in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.
  • Sequence similaritiesBelongs to the aldo/keto reductase family.
  • Cellular localizationCytoplasm.

    • Target information above from: UniProt accession P52895 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    AKR1C2 protein images

    • SDS-PAGE - AKR1C2 protein (ab114784)
      SDS-PAGE - AKR1C2 protein (ab114784)
      ab114784 on 12.5% SDS-PAGE Stained with Coomassie Blue.

    References for AKR1C2 protein (ab114784)

    ab114784 has not yet been referenced specifically in any publications.

    Publishing research using ab114784 ? Please let us know so that we can cite the reference in this datasheet

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