Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Cardiovascular >> Hypoxia >> Hypoxia-Regulated
Overview
Product name
ALAS2 protein (His tag)
Protein description
Recombinant fragment corresponding to amino acids 136-553 of Human ALAS2 with N terminal His tag, 46 kDa. Swiss ID = P22557
Expression host
E. coli
Properties
Purity
>90% by SDS-PAGE
Form
Liquid
Storage instructions
Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 20% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, 20 µM pyridoxal 5' phosphate monohydrate pH 8.0
Concentration
Concentration information loading...
Research areas
Cancer >> Cancer Metabolism >> Response to hypoxia
Cardiovascular >> Blood >> Erythrocytes
Signal Transduction >> Metabolism >> Mitochondrial
Signal Transduction >> Metabolism >> Amino Acids
Cardiovascular >> Hypoxia >> Hypoxia-Regulated
-
SDS-PAGE - ALAS2 protein (His tag) (ab79941)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab79941 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
SDS-PAGE
Application notes
SDS-PAGE: Use at an assay dependent dilution.
ab79941 is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Protein info
Relevance
ALAS2 specifies an erythroid-specific mitochondrially located enzyme. It catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
Cellular localization
Mitochondrion matrix.
ALAS2 protein (His tag) images:
SDS-PAGE - ALAS2 protein (His tag) (ab79941)
105 SDS-PAGE showing ab79941 at approximately 46kDa (8µg).
References for ALAS2 protein (His tag) (ab79941)
ab79941 has not yet been referenced specifically in any publications.
Publishing research using ab79941? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"