Anti-ALDH1L2 antibody (ab113496)
Key features and details
- Rabbit polyclonal to ALDH1L2
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ALDH1L2 antibody
See all ALDH1L2 primary antibodies -
Description
Rabbit polyclonal to ALDH1L2 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Recombinant fragment, corresponding to amino acids 2-247 of Human ALDH1L2 (BC103935).
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Positive control
- Human Fetal Kidney, Human Fetal Heart, and Human Fetal Liver lysates, Human Fetal Heart tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Lyophilized:Reconstitute in 200ul sterile H2O. -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituent: 1% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab113496 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000 - 1/2000. Predicted molecular weight: 102 kDa.
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IHC-P |
1/100 - 1/500.
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Notes |
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WB
1/1000 - 1/2000. Predicted molecular weight: 102 kDa. |
IHC-P
1/100 - 1/500. |
Target
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Sequence similarities
In the N-terminal section; belongs to the GART family.
In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
Contains 1 acyl carrier domain. - Information by UniProt
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Database links
- Entrez Gene: 160428 Human
- Entrez Gene: 216188 Mouse
- Entrez Gene: 299699 Rat
- Omim: 613584 Human
- SwissProt: Q3SY69 Human
- SwissProt: Q8K009 Mouse
- Unigene: 42572 Human
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Alternative names
- 10 formyltetrahydrofolate dehydrogenase ALDH1L2 antibody
- 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE, MITOCHONDRIAL antibody
- AL1L2_HUMAN antibody
see all
Images
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All lanes : Anti-ALDH1L2 antibody (ab113496) at 1/1000 dilution
Lane 1 : Human Fetal Kidney Lysate
Lane 2 : Human Fetal Heart Lysate
Lane 3 : Human Fetal Liver Lysate
Predicted band size: 102 kDa -
Staining of Human ALDH1L2 in a Formalin/PFA-fixed paraffin-embedded section of Human Fetal Heart using ab113496 at a dilution of 1/100.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab113496 has been referenced in 3 publications.
- Lee JS et al. Overall survival of pancreatic ductal adenocarcinoma is doubled by Aldh7a1 deletion in the KPC mouse. Theranostics 11:3472-3488 (2021). PubMed: 33537098
- Lee JS et al. Gastric cancer depends on aldehyde dehydrogenase 3A1 for fatty acid oxidation. Sci Rep 9:16313 (2019). PubMed: 31705020
- Zheng Y et al. Mitochondrial One-Carbon Pathway Supports Cytosolic Folate Integrity in Cancer Cells. Cell 175:1546-1560.e17 (2018). PubMed: 30500537