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Product name Anti-ALDH5A1 antibody See all ALDH5A1 primary antibodies
Rabbit polyclonal to ALDH5A1
Tested applications Suitable for:
WB, ELISA more details
Mouse, Rat, Human
Synthetic 22 amino acid peptide from near the C terminus of Human ALDH5A1 (NP_733936).
Mouse liver tissue lysate.
Storage instructions Shipped at 4°C. Store at +4°C.
Storage buffer Preservative: 0.02% Sodium Azide
Concentration information loading...
Purity Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 57 kDa.
Use at an assay dependent dilution.
Function Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
Tissue specificity Brain, pancreas, heart, liver, skeletal muscle and kidney. Lower in placenta.
Pathway Amino-acid degradation; 4-aminobutanoate degradation.
Involvement in disease Defects in ALDH5A1 are the cause of succinate semialdehyde dehydrogenase deficiency (SSADH deficiency) [MIM:271980]. SSADH deficiency is a rare inborn error in the metabolism of 4-aminobutyric acid (GABA) which leads to accumulation of 4-hydroxybutyric acid in physiologic fluids of patients. The disease is characterized by severe ataxia and by mildly retarded psychomotor development.
Sequence similarities Belongs to the aldehyde dehydrogenase family.
Cellular localization Mitochondrion.
Information by UniProt
Aldedehyde dehydrogenase 5 family antibody
Aldehyde dehydrogenase 5 family member A1 antibody
Aldehyde dehydrogenase 5A1 antibody
Anti-ALDH5A1 antibody images
Western blot - ALDH5A1 antibody (ab77078)
Lane 1 : Anti-ALDH5A1 antibody (ab77078) at 1 µg/ml Lane 2 : Anti-ALDH5A1 antibody (ab77078) at 2 µg/ml Lane 1 : Mouse liver lysate Lane 2 : Mouse liver lysate Lysates/proteins at 15 µg per lane. Predicted band size : 57 kDa Observed band size : 57 kDa Additional bands at : 60 kDa,>90 kDa. We are unsure as to the identity of these extra bands.
References for Anti-ALDH5A1 antibody (ab77078)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"