Overview

  • Product nameAnti-ALS2CR2 antibodySee all ALS2CR2 primary antibodies ...
  • Description
    Goat polyclonal to ALS2CR2
  • SpecificityThis is expected to recognise both human isoforms: ILPIP alpha (NP_061041) and ILPIP beta (AAF71042).
  • Tested applicationsIHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    CDFPDEKDSYWEF

    , corresponding to amino acids 406-418 of Human ALS2CR2.

  • Positive control
    • Human heart or liver lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab4122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 47 kDa).Can be blocked with Human ALS2CR2 peptide (ab22984).

Target

  • FunctionPseudokinase which, in complex with CAB39, binds to and activates STK11. Relocates STK11 from the nucleus to the cytoplasm. Plays an essential role in STK11-mediated G1 cell cycle arrest.
  • Tissue specificityHighly expressed in heart, skeletal muscle, testis, liver and colon.
  • Sequence similaritiesBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 protein kinase domain.
  • DomainThe protein kinase domain is predicted to be catalytically inactive.
  • Cellular localizationNucleus. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 2 antibody
    • Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein antibody
    • CALS 21 antibody
    • CALS-21 antibody
    • ILP interacting protein ILPIPA antibody
    • ILP-interacting protein antibody
    • ILPIP antibody
    • ILPIPA antibody
    • Likely ortholog of mouse polyploidy associated protein kinase antibody
    • PAPK antibody
    • PRO1038 antibody
    • Pseudokinase ALS2CR2 antibody
    • STE20-related kinase adapter protein beta antibody
    • STRAB_HUMAN antibody
    • STRAD beta antibody
    • STRADB antibody
    see all

Anti-ALS2CR2 antibody images



  • Predicted band size : 47 kDa


    ab4122 at a concentration of 1µg/ml staining ALS2CR2 in human heart lysate (RIPA buffer, 30µg total protein per lane) by Western blot. Primary incubated for 1 hour and detected by chemiluminescence.
  • ab4122 (3.8 µg/ml) staining ALS2CR2 in myocardial fibers in a transverse section of paraffin-embedded human heart following steamed antigen retrieval with citrate buffer pH6.

References for Anti-ALS2CR2 antibody (ab4122)

ab4122 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab4122.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"