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Anti-AMACR antibody (ab15893)

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Overview

Product name

Anti-AMACR antibody
See all AMACR products (9) ...

Description

Rabbit polyclonal to AMACR

Tested applications

Immunomicroscopy, WBmore details

Cross reactivity

Reacts with

Mouse, Rat, Human

Immunogen

Synthetic peptide: GAAVLRRLCKRSDVLLEPFR , corresponding to amino acids 62-81 of Human AMCR.

GAAVLRRLCK RSDVLLEPFR

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Epitope

ab15893 recognises a unique epitope that is present on AMCR I and II variants

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Cell Biology >> Other Antibodies >> Oxidative Stress
Signal Transduction >> Metabolism >> Lipid metabolism
Epigenetics and Nuclear Signaling >> Transcription >> Cancer susceptibility >> Proto-oncogenes
Signal Transduction >> Metabolism >> Mitochondrial
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated

Applications

Show applications key

Our Abpromise guarantee covers the use of ab15893 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Immunomicroscopy

     

  • WB

     

Application notes

IM: Use at an assay dependent dilution.
WB: 1/500. Ab15893 strongly labels bands at 32 and 42 kDa corresponding to AMCR I and II variants.

Does not work well with IHC.

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

AMARC has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMARC protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.

Cellular localization

Mitochondrial, Peroxisome

Alternative names

  • 2 arylpropionyl CoA epimerase antibody
  • 2 methylacyl CoA racemase antibody
  • Alpha methylacyl CoA racemase antibody
  • Alpha methylacyl Coenzyme A racemase antibody
  • Alpha methylacyl-CoA racemase deficiency, included antibody
  • Alpha-methylacyl-CoA racemase antibody
  • AMACR deficiency, included antibody
  • CBAS4 antibody
  • Da1-8 antibody
  • EC 5.1.99.4 antibody
  • Macr 1 antibody
  • Macr1 antibody
  • Methylacyl CoA racemase alpha antibody
  • P504S antibody
  • RACE antibody
  • RM antibody
see all

Database links

References for Anti-AMACR antibody (ab15893)

ab15893 has not yet been referenced specifically in any publications.

Publishing research using ab15893? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"