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Anti-AMACR antibody (ab15894)

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Overview

Product name

Anti-AMACR antibody
See all AMACR products (9) ...

Description

Rabbit polyclonal to AMACR

Specificity

Ab15894 is specific for AMCR I

Tested applications

WB, Immunomicroscopymore details

Cross reactivity

Reacts with

Mouse, Human

Immunogen

Synthetic peptide: TDACVTPVLTFEEWHHD, corresponding to amino acids 290-307 of Human AMACR

TDACVTPVLT FEEWHHD

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: BSA

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Purification notes

Affinity purified against immobilized antigen. Supplied as a pure IgG fraction.

Clonality

Polyclonal

Isotype

IgG

Research areas

Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Cell Biology >> Other Antibodies >> Oxidative Stress
Signal Transduction >> Metabolism >> Lipid metabolism
Epigenetics and Nuclear Signaling >> Transcription >> Cancer susceptibility >> Proto-oncogenes
Signal Transduction >> Metabolism >> Mitochondrial
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated

Applications

Show applications key

Our Abpromise guarantee covers the use of ab15894 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • WB

     

  • Immunomicroscopy

     

Application notes

IM: Use at an assay dependent dilution.
WB: 1/500. Predicted molecular weight: 42 kDa corresponding to variant AMCR I.

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

AMARC has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMARC protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.

Cellular localization

Mitochondrial, Peroxisome

Alternative names

  • 2 arylpropionyl CoA epimerase antibody
  • 2 methylacyl CoA racemase antibody
  • Alpha methylacyl CoA racemase antibody
  • Alpha methylacyl Coenzyme A racemase antibody
  • Alpha methylacyl-CoA racemase deficiency, included antibody
  • Alpha-methylacyl-CoA racemase antibody
  • AMACR deficiency, included antibody
  • CBAS4 antibody
  • Da1-8 antibody
  • EC 5.1.99.4 antibody
  • Macr 1 antibody
  • Macr1 antibody
  • Methylacyl CoA racemase alpha antibody
  • P504S antibody
  • RACE antibody
  • RM antibody
see all

Database links

References for Anti-AMACR antibody (ab15894)

ab15894 has not yet been referenced specifically in any publications.

Publishing research using ab15894? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"