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Western blot - AMFR antibody (ab54787)
(enlarge)
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Product Name
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AMFR antibody
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See all AMFR antibodies (4)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to AMFR
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Immunogen
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Recombinant fragment: QASNSQLNAM AHQIQEMFPQ VPYHLVLQDL QLTRSVEITT DNILEGRIQV PFPTQRSDSI RPALNSPVER PSSDQEEGET SAQTERVPLD LSPRLEETLD , corresponding to amino acids 451-551 of Human AMFR
BLAST 'QASNSQLNAM AHQIQEMFPQ VPYHLVLQDL QLTRSVEITT DNILEGRIQV PFPTQRSDSI RPALNSPVER PSSDQEEGET SAQTERVPLD LSPRLEETLD ' with  or 
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Reacts with
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RecFrag
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Predicted to react
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Hu
(Due to sequence homology)
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Tested applications
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Single-pass type I membrane protein.
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Research areas
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Cancer >> Tumor biomarkers >> Other
Cell Biology >> Proteolysis / Ubiquitin >> Proteasome / Ubiquitin >> Ubiquitin E2s and E3s >> RING Finger E3 Ligase
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Relevance
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AMFR (Autocrine motility factor receptor, isoform 2) is specific receptor for the autocrine motility factor. AMFR possesses ubiquitin ligase activity and can target both itself and other proteins including CD3D and APOB for proteasomal degradation. AMFR mediates tumor invasion and metastasis. The protein interacts with UBE2G2/UBC7 through a region distinct from the RING finger.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG2a
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this AMFR antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for AMFR antibody images, references, products related to ab54787 and other tools.
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AMFR antibody images:
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 Western blot - AMFR antibody (ab54787)
Western blot against tagged recombinant protein immunogen using ab54787 AMFR antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
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Search PubMed (MEDLINE) for references to AMFR
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AMFR antibody - more information
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Customer reviews (feedback) regarding AMFR antibody |
Customer FAQs regarding AMFR antibody |
Protocols for AMFR antibody |
Price and availability of products related to AMFR antibody |
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AMFR antibody - related products:
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AMFR antibody - other tools:
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Contact Abcam with a Technical Enquiry about AMFR antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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