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Anti-AMH antibody (ab84952)

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Overview

Product name

Anti-AMH antibody
See all AMH products (4) ...

Description

Rabbit polyclonal to AMH

Tested applications

WB, IHC-Pmore details

Cross reactivity

Reacts with

Human

Predicted to work with

Mouse, Rat, Cow, Dog, Pig

Immunogen

Synthetic peptide corresponding to a region within internal sequence amino acids 468-517 (SVDLRAERSV LIPETYQANN CQGVCGWPQS DRNPRYGNHV VLLLKMQARG) of Human AMH (NP_000470).

SVDLRAERSV LIPETYQANN CQGVCGWPQS DRNPRYGNHV VLLLKMQARG

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

Human fetal small intestine lysate.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 2% Sucrose, PBS

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Developmental Biology >> Reproduction >> Placental development
Developmental Biology >> Reproduction >> Sex determination
Stem Cells >> Signaling Pathways >> TGF beta >> Secreted
Signal Transduction >> Growth Factors/Hormones >> TGF

  • Western blot - AMH antibody (ab84952)Western blot - AMH antibody (ab84952) image (enlarge)

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AMH antibody (ab84952)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AMH antibody (ab84952) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab84952 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.

Cellular localization

Secreted

Alternative names

  • Anti muellerian hormone antibody
  • MIF antibody
  • MIS antibody
  • Muellerian inhibiting factor antibody
  • Mullerian inhibiting substance antibody
see all

Database links

see all

Anti-AMH antibody images:

  Western blot - AMH antibody (ab84952)

Western blot - AMH antibody (ab84952)

Anti-AMH antibody (ab84952) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal small intestine lysate at 10 µg

Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution

Predicted band size : 60 kDa
Observed band size : 65 kDa (why is the actual band size different from the predicted?)


Gel concentration: 12%

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AMH antibody (ab84952)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AMH antibody (ab84952)

ab84952 staining AMH in human prostate tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).

References for Anti-AMH antibody (ab84952)

ab84952 has not yet been referenced specifically in any publications.

Publishing research using ab84952? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"