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Anti-AMHR2 antibody - Aminoterminal end (ab75845)

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Overview

Product name

Anti-AMHR2 antibody - Aminoterminal end
See all AMHR2 products (3) ...

Description

Rabbit polyclonal to AMHR2 - Aminoterminal end

Tested applications

WB, ELISAmore details

Cross reactivity

Reacts with

Human

Immunogen

KLH conjugated synthetic peptide selected from the N terminal region of human AMHR2.

Positive control

Transfected 293 cell lysates.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 0.09% Sodium Azide
Constituents: PBS

Concentration

Concentration information loading...

Purity

Ammonium Sulphate Precipitation

Purification notes

This antibody is prepared by Saturated Ammonium Sulfate precipitation followed by dialysis against PBS.

Clonality

Polyclonal

Isotype

IgG

  • Western blot - AMHR2 antibody - Aminoterminal end (ab75845)Western blot - AMHR2 antibody - Aminoterminal end (ab75845) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab75845 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide1 Image

    WB

     WB: 1/50 - 1/100.Predict...Read more →

    WB: 1/50 - 1/100.Predicted molecular weight: 63 kDa.

  • ELISA

     ELISA: 1/1000

    ELISA: 1/1000

Target

Function

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.

Involvement in disease

Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS2) [MIM:261550]. PMDS2 is a form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.

Sequence similarities

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Contains 1 protein kinase domain.

Cellular localization

Membrane.

Target information above from: UniProt accessionQ16671 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • AMH type II receptor antibody
  • AMHR2 antibody
  • AMHR2_HUMAN antibody
  • Anti-Muellerian hormone type II receptor antibody
  • Anti-Muellerian hormone type-2 receptor antibody
  • MGC141312 antibody
  • MIS type II receptor antibody
  • MISRII antibody
  • MRII antibody
  • Muellerian hormone type 2 receptor antibody
  • Muellerian hormone type II receptor antibody
  • Mullerian hormone receptor type II antibody
see all

Anti-AMHR2 antibody - Aminoterminal end images:

  Western blot - AMHR2 antibody - Aminoterminal end (ab75845)

Western blot - AMHR2 antibody - Aminoterminal end (ab75845)

All lanes : Anti-AMHR2 antibody - Aminoterminal end (ab75845) at 1/50 dilution

Lane 1 : Non transfected 293 cell lysates
Lane 2 : Transiently transfected 293 cell lysates

Lysates/proteins at 2 µg per lane.


Predicted band size : 63 kDa
Observed band size : 63 kDa

References for Anti-AMHR2 antibody - Aminoterminal end (ab75845)

ab75845 has not yet been referenced specifically in any publications.

Publishing research using ab75845? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"