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Western blot - AMHR2 antibody - Aminoterminal end (ab75845)
Western blot - AMHR2 antibody - Aminoterminal end (ab75845)
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Product Name 

AMHR2 antibody - Aminoterminal end

 

See all AMHR2 antibodies (2)...

Product type 

Primary antibodies

Description 

Rabbit polyclonal to AMHR2 - Aminoterminal end

Immunogen 

KLH conjugated synthetic peptide selected from the N terminal region of human AMHR2.

Reacts with 
(species key)

Hu

Tested applications 
(see key)

ELISA, WB


Abreviews 

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Application notes 
(see key)

Recommended dilutions
ELISA: 1/1000.
WB: 1/50 - 1/100. Predicted molecular weight: 63 kDa.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Transfected 293 cell lysates.

Cellular localization 

Plasma membrane

Research areas 

Stem Cells >> Signaling Pathways >> TGF beta >> Surface Molecules
Signal Transduction >> Growth Factors/Hormones >> TGF
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> Other Kinases

Relevance 

AMHR2 is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins that is expressed in fetal and adult gonads of both sexes. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. A number of allelic variants of AMHR2 are assoicated with persistent mullerian duct syndrome.

 

Alternative names AMHR2 antibody - Aminoterminal end (ab75845)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

269    (Human)

Omim

    

600956    (Human)

SwissProt

    

Q16671    (Human)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Ammonium Sulphate Precipitation

Storage buffer 

Preservative: 0.09% Sodium Azide
Constituents: PBS

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Purification notes 

This antibody is prepared by Saturated Ammonium Sulfate precipitation followed by dialysis against PBS.

Form 

Liquid

Concentration 

0.250 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this AMHR2 antibody - Aminoterminal end is on this datasheet. But please do contact us if you would like any reassurance!


See below for AMHR2 antibody - Aminoterminal end images, references, products related to ab75845 and other tools.

 

AMHR2 antibody - Aminoterminal end images:

Product image  Western blot - AMHR2 antibody - Aminoterminal end (ab75845)

Western blot - AMHR2 antibody - Aminoterminal end (ab75845)

All lanes : AMHR2 antibody - Aminoterminal end (ab75845) at 1/50 dilution

Lane 1 : Non transfected 293 cell lysates
Lane 2 : Transiently transfected 293 cell lysates

Lysates/proteins at 2 µg per lane.


Predicted band size : 63 kDa
Observed band size : 63 kDa

 
 

Search PubMed (MEDLINE) for references to AMHR2

 

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