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Western blot - AMHR2 antibody - Aminoterminal end (ab75845)
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Product Name
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AMHR2 antibody - Aminoterminal end
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See all AMHR2 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to AMHR2 - Aminoterminal end
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Immunogen
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KLH conjugated synthetic peptide selected from the N terminal region of human AMHR2.
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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ELISA, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: 1/1000.
WB: 1/50 - 1/100. Predicted molecular weight: 63 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Transfected 293 cell lysates.
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Cellular localization
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Plasma membrane
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Research areas
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Stem Cells >> Signaling Pathways >> TGF beta >> Surface Molecules
Signal Transduction >> Growth Factors/Hormones >> TGF
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> Other Kinases
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Relevance
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AMHR2 is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins that is expressed in fetal and adult gonads of both sexes. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. A number of allelic variants of AMHR2 are assoicated with persistent mullerian duct syndrome.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Ammonium Sulphate Precipitation
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Storage buffer
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Preservative: 0.09% Sodium Azide
Constituents: PBS Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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This antibody is prepared by Saturated Ammonium Sulfate precipitation followed by dialysis against PBS.
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Form
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Liquid
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Concentration
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0.250 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this AMHR2 antibody - Aminoterminal end is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for AMHR2 antibody - Aminoterminal end images, references, products related to ab75845 and other tools.
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AMHR2 antibody - Aminoterminal end images:
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 Western blot - AMHR2 antibody - Aminoterminal end (ab75845)
All lanes : AMHR2 antibody - Aminoterminal end (ab75845) at 1/50 dilution
Lane 1 : Non transfected 293 cell lysates
Lane 2 : Transiently transfected 293 cell lysates
Lysates/proteins at 2 µg per lane.
Predicted band size : 63 kDa
Observed band size : 63 kDa
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Search PubMed (MEDLINE) for references to AMHR2
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