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Product Name
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AMHR2 antibody [MIG7]
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See all AMHR2 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [MIG7] to AMHR2
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Immunogen
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Synthetic peptide: GTELPRAIRCLYSR, corresponding to amino acids 46-59 of Human AMHR2 conjugated with hsp70.
BLAST 'GTELPRAIRCLYSR' with  or 
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Reacts with
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Hu, Rat
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Predicted to react
(species key)
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Rb
(Due to sequence homology)
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Specificity
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Recognizes human cells bearing AMHR2 extracellular domain.
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Tested applications
(see key)
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I-ELISA, ICC/IF, IHC-P, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ICC/IF: Use at an assay dependent dilution.
IHC-P: 1/500. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
I-ELISA: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 63 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Plasma membrane
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Research areas
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Stem Cells >> Signaling Pathways >> TGF beta >> Surface Molecules
Signal Transduction >> Growth Factors/Hormones >> TGF
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> Other Kinases
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Relevance
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AMHR2 is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins that is expressed in fetal and adult gonads of both sexes. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. A number of allelic variants of AMHR2 are assoicated with persistent mullerian duct syndrome.
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AMHR2 antibody [MIG7] (ab64762) |
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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MIG7
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Myeloma
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Sp2/0
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Isotype
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IgG1
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Purity
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Protein G purified
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Storage buffer
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Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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2.000 mg/ml
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this AMHR2 antibody [MIG7] is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to AMHR2
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AMHR2 antibody [MIG7] - more information
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Customer FAQs regarding AMHR2 antibody [MIG7] |
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